Replacement of bioprostheses after structural valve deterioration

  • Charles A. Yankah
  • M. Pasic
  • Henryk Siniawski
  • J. Stein
  • C. Detschades
  • A. Unbehaun
  • N. Solowjowa
  • S. Buz
  • Y. Weng
  • Roland Hetzer


Xenografts, allografts, and pulmonary autografts have complimentary roles in the treatment of valvular heart diseases. Because the recipients require no long-term anticoagulant therapy, the incidence of thromboembolic events is low in contrast to that in mechanical valve recipients [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14]. Furthermore, among the biological valves, the allograft has an additional advantage over xenografts and mechanical valves for aortic valve replacement in the setting of endocarditis, with a lower probability of recurrent infections [15, 16, 17, 18, 19, 20]. Another purported advantage of biological prostheses (BP) is their anticipated subtle mode of failure in contrast to the catastrophic mechanism of failure anticipated for mechanical prostheses. Despite the obvious advantage of bioprostheses over the mechanical valves some surgeons still favor the mechanical prosthesis (MP) because of its high structural durability and lower reoperation rate for younger patients [21, 22]. The mechanical prosthesis, however, poses a contraindication in elderly and noncompliant patients because of the valve-related hemorrhagic and thromboembolic complications.


Coronary Artery Bypass Grafting Aortic Valve Replacement Mechanical Valve Prosthetic Valve Endocarditis Mechanical Prosthesis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Charles A. Yankah
    • 1
  • M. Pasic
  • Henryk Siniawski
    • 1
  • J. Stein
  • C. Detschades
  • A. Unbehaun
  • N. Solowjowa
  • S. Buz
  • Y. Weng
  • Roland Hetzer
    • 1
  1. 1.Deutsches Herzzentrum Berlin & Charité Medical University BerlinBerlinGermany

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