Edwards Prima Plus Stentless Bioprosthesis: Long-term clinical and hemodynamic results

  • Alessandro Fabbri
  • A. D’Onofrio
  • S. Auriemma
  • G. D. Cresce
  • C. Piccin
  • A. Favaro
  • P. Magagna


Stentless aortic xenografts were introduced into clinical practice in order to improve clinical outcomes following aortic valve replacement for their better hemodynamic performance and durability. Edwards Lifesciences Prima Plus stentless xenograft (EPP) (Edwards Lifesciences, Irvine, CA, USA) is a bioprosthesis made of a porcine aortic root reinforced with Dacron fabric.


Aortic Root Aortic Valve Replacement Coronary Ostium Hemodynamic Result Small Aortic Annulus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Auriemma S, D’Onofrio A, Brunelli M, Magagna P, Paccanaro M, Rulfo F, Fabbri A (2006) Long-term results of aortic valve replacement with Edwards Prima Plus stentless bioprosthesis: eleven years’ follow up. J Heart Valve Dis 15(5):691–695, discussion 695PubMedGoogle Scholar
  2. 2.
    Konertz W, Hamann P, Schwammenthal E et al (1992) Aortic valve replacement with stentless xenografts. J Heart Valve Dis 1:249–252PubMedGoogle Scholar
  3. 3.
    Westaby S, Katsumata T, Arifi A et al. (1996) Valve replacement with a stentless biprosthesis: versatility of the porcine aortic root. J Thorac Cardiovasc Surg 112: 708–711CrossRefGoogle Scholar
  4. 4.
    Edmunds LH Jr, Clark RE, Cohn LH et al (1996) Guidelines for reporting morbidity and mortality after cardiac valvular operations. Ann Thorac Surg 62:932–935CrossRefPubMedGoogle Scholar
  5. 5.
    Binet JP, Carpentier A, Langlois J (1965) Heterologous aortic valve transplantation. Lancet 2:1275CrossRefPubMedGoogle Scholar
  6. 6.
    Angell WW, Angell JD, Oury JH et al (1987) Long-term follow-up of viable frozen aortic homografts: a viable homograft valve bank. J Thorac Cardiovasc Surg 93: 815–822PubMedGoogle Scholar
  7. 7.
    O’Brien MF, Clareborough JK (1967) Heterograft aortic-valve replacement. Lancet 1(7496):929–930CrossRefPubMedGoogle Scholar
  8. 8.
    Binet JP, Carpentier A, Langlois J (1968) Clinical use of heterografts for replacement of the aortic valve. J Thorac Cardiovasc Surg 55(2):238–242PubMedGoogle Scholar
  9. 9.
    David TE, Bos J, Rakowski H (1988) aortic valve replacement with the Toronto SPV bioprosthesis. J Cardiac Surg 3:501–505CrossRefGoogle Scholar
  10. 10.
    Luciani GB (2004) Stentless aortic valve replacement: current status and future trends. Expert Rev Cardiovasc Ther 2(1):127–140CrossRefPubMedGoogle Scholar
  11. 11.
    Desai ND, Gideon OM, Cohen N et al (2004) Long-term results of aortic valve replacement with the St Jude Toronto Stentless Porcine Valve. Ann Thorac Surg 78:2076–2083CrossRefPubMedGoogle Scholar
  12. 12.
    Vanermen H, Dossche K, Daenen W et al (1995) Early results of the Edwards Prima stentless aortic bioprosthesis in 200 patients. In: Piwnica A, Westaby S (eds) Stentless bioprosthesis. Eur J Cardiothorac Surg 9:562–567Google Scholar
  13. 13.
    Bortolotti U, Scioti G, Milano A et al (1999) The Edwards Prima stentless valve: Hemodinamic performance at one year. Ann Thorac Surg 68:2147–2151CrossRefPubMedGoogle Scholar
  14. 14.
    Westaby S, Amarasena N, Long V et al (1995) Time-related hemodinamic changes after aortic replacement with the Freestyle stentless xenograft. Ann Thorac Surg 60:1633–1639CrossRefPubMedGoogle Scholar
  15. 15.
    D’Onofrio A, Auriemma S, Magagna P, Abbiate N, Fabbri A (2008) The inclusion technique reduces ischemia after stentless aortic root replacement. Ann Thorac Surg 85:1143–1144CrossRefPubMedGoogle Scholar
  16. 16.
    Kincaid EH, Cordell AR, Hammon JW, Adair SM, Kon ND (2007) Coronary insufficiency after stentless aortic root replacement: risk factors and solutions Ann Thorac Surg 83:964–968CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Alessandro Fabbri
    • 1
  • A. D’Onofrio
  • S. Auriemma
  • G. D. Cresce
  • C. Piccin
  • A. Favaro
  • P. Magagna
  1. 1.Division of Cardiac SurgerySan Bortolo Vicenza HospitalVicenzaItaly

Personalised recommendations