Repair of rheumatic mitral valve incompetence: surgical challenges and clinical results

  • C.A. Yankah
  • H. Siniawski
  • R. Hetzer


Rheumatic heart valve disease (RHVD) is one of the sequelae of rheumatic fever (RF) triggered by autoimmune humoral and cellular responses and remains the predominant heart valve disease in developing countries. It is seen in epidemic proportions in the preschool and school age groups but is also found in patients in their teens and early twenties. The youngest patient reported was 2 years old. In addition, a number of patients present during adulthood at a mean age of 40 years in developing countries and in their early 50s and 60s in developed countries. Rheumatic heart valve disease has become rare, virtually nonexistent in most affluent populations, but remains uncontrolled in developing countries with an incidence of 1.6/1000 in Liberia, 2.2/1000 in Cambodia, and 2.3/1000 in Mozambique, as determined by clinical diagnosis without echocardiograhic support. The global burden is estimated to be 15.6 million and about 282,000 new cases are registered each year with an annual mortality of 233,000.


Mitral Valve Mitral Regurgitation Rheumatic Fever Rheumatic Heart Disease Mitral Valve Repair 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • C.A. Yankah
    • 1
  • H. Siniawski
    • 2
  • R. Hetzer
    • 2
  1. 1.Consultant Cardiothoracic & Vascular Surgeon Deutsches Herzzentrum BerlinCharité Medical University BerlinBerlinGermany
  2. 2.Deutsches Herzzentrum BerlinCharité Medical University BerlinBerlinGermany

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