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Rationale for Type of Resection in Cancer of the Esophagus and Gastroesophageal Junction

  • Wolfram T. Knoefel
  • Ingo Alldinger
  • Jakob R. Izbicki

Abstract

Despite new insights into its molecular basis and various treatment options evaluated in numerous trials, therapy of esophageal cancer remains a challenge. In the past, surgery was the only treatment option. A patient qualified for surgery when he presented in stable condition and when the tumor was believed to be resectable. Today a vast number of treatment strategies, including induction chemotherapy, radiochemotherapy with or without combination with surgery, administered in an adjuvant or a neoadjuvant setting, are added to the traditional therapy of surgery alone. Even the question, whether surgery after effective chemoradiation does have any impact on prognosis at all or is no more than a “big biopsy” is discussed today. There is increasing evidence that patients may benefit from induction chemotherapy.

Keywords

Esophageal Cancer Esophageal Carcinoma Gastroesophageal Junction Oesophageal Cancer Celiac Trunk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Steinkopff Verlag 2009

Authors and Affiliations

  • Wolfram T. Knoefel
    • 1
  • Ingo Alldinger
    • 1
  • Jakob R. Izbicki
    • 2
  1. 1.Department of General-, Visceral- and Pediatric SurgeryHeinrich-Heine-University of DüsseldorfDüsseldorfGermany
  2. 2.Department of General, Visceral and Thoracic SurgeryUniversity Hospital Hamburg EppendorfHamburgGermany

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