Lymphatic Dissemination and Principles of Lymph Node Dissection

  • Jakob R. Izbicki
  • Alexander Rehders
  • Asad Kutup
  • Christoph Busch


Throughout the last decades the results of surgical treatment on esophageal cancer have improved continuously. Before 1980 Isono [1] reported a 5-year survival rate of 12.4%. In this study he describes the mode of recurrence after esophagectomy: 13.0% of patients had local recurrence, 8.7% had recurrence in the residual esophagus, 43.5% had evidence of lymph node metastasis, 28.3% had recurrence in other organs, and 6.5% had pleural or peritoneal tumor dissemination. The relapse pattern in lymph nodes showed recurrence in cervical nodes in 21.7%, mediastinal nodes in 19.6%, and abdominal nodes in 2.2%. These results suggest that extensive surgery with radical lymph node dissection could bear a chance of cure for these patients.


Esophageal Cancer Laryngeal Nerve Celiac Trunk Left Gastric Artery Esophageal Hiatus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Steinkopff Verlag 2009

Authors and Affiliations

  • Jakob R. Izbicki
    • 1
  • Alexander Rehders
    • 2
  • Asad Kutup
    • 1
  • Christoph Busch
    • 1
  1. 1.Department of General, Visceral and Thoracic SurgeryUniversity Hospital Hamburg EppendorfHamburgGermany
  2. 2.Department of General-, Visceral- and Pediatric SurgeryHeinrich-Heine-University of DüsseldorfDüsseldorfGermany

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