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Septisches Lungenversagen

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Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen

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Sowohl die primäre Infektion der Lunge als auch deren inflammatorische Mitreaktion bei extrapulmonalem Sepsisherd können Ursachen des septischen Lungenversagens sein, das eine über die Jahre unverändert hohe Sterblichkeit aufweist. Dazu kann eine beatmungsinduzierte Lungenschädigung (VALI) das septische Lungenversagen aggravieren. Neben der kausalen Therapie der Sepsis stehen für die Behandlung des septischen Lungenversagens Maßnahmen zur Verfügung, die von der Flüssigkeitsrestriktion über die 4-Seitenlagerung bis hin zur protektiven Beatmung reichen. Protektive Beatmung umfasst niedrige Tidalvolumina, permissive Hyperkapnie, inspiratorische Plateaudrücke unter 30 cm H2O und erhöhten PEEP.

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  1. Einheit für Multidisziplinäre Intensivmdizin, Universitätsklinikum Leipzig A.ö.R, Liebigstraße 20, 04103, Leipzig, Germany

    Prof. Dr. Lothar Engelmann

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  1. Einheit für Multidisziplinäre Intensivmedizin (EMI), Universitätsklinikum Leipzig AÖR, Liebigstr. 20, 04104, Leipzig

    Lothar Engelmann

  2. Klinikum Hildesheim, Weinberg 1, 31134, Hildesheim

    Hans-Peter Schuster

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Engelmann, L. (2006). Septisches Lungenversagen. In: Engelmann, L., Schuster, HP. (eds) Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen. Steinkopff. https://doi.org/10.1007/978-3-7985-1729-5_9

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