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Antibiotika bei Sepsis und Multiorganversagen

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Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen

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Nosokomiale Infektionen nehmen weltweit zu. Die Häufigkeitsverteilung unterscheidet sich zwischen dem Gesamtkrankenhaus und den Intensivstationen, wo die intubationsassoziierten Pneumonien nach wie vor die größte infektiologische Herausforderung darstellen. Je nach individuellen Risikofaktoren und Art der Infektion kann die Letalität bei 30–70% liegen. Eine der Hauptrisikofaktoren für diese hohe Sterblichkeit ist die inadäquate antimikrobielle Therapie. Entscheidend für die Prognose ist eine rasche und möglichst das gesamte potentielle Erregerspektrum erfassende empirische Initialtherapie. Für diese Therapie sind folgende Einzelaspekte der sog.

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Authors and Affiliations

  1. Klinik für Anaesthesiologie, Intensivmedizin und Schmerztherapie Knappschaftskrankenhaus Bochum-Langendreer Universitätsklinik, In der Schornau 23–25, 44892, Bochum, Germany

    Prof. Dr. med. Eckhard Müller

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  1. Einheit für Multidisziplinäre Intensivmedizin (EMI), Universitätsklinikum Leipzig AÖR, Liebigstr. 20, 04104, Leipzig

    Lothar Engelmann

  2. Klinikum Hildesheim, Weinberg 1, 31134, Hildesheim

    Hans-Peter Schuster

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Müller, E. (2006). Antibiotika bei Sepsis und Multiorganversagen. In: Engelmann, L., Schuster, HP. (eds) Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen. Steinkopff. https://doi.org/10.1007/978-3-7985-1729-5_5

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