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Sepsis und Akutes Nierenversagen

Nephroprotektion und Einsatz von Nierenersatzverfahren

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Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen

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Das akute Nierenversagen (ANV) ist eine häufige Komplikation der Sepsis, die den Verlauf entscheidend beeinflusst. Mehr als die Hälfte der Patienten mit septischem Schock weisen ein ANV auf und noch bei 20% aller Patienten mit moderater Sepsis, ist ein solches nachzuweisen. Septische Patienten mit ANV weisen eine signifikant höhere Letalität, als diejenigen Patienten mit ANV ohne Sepsis auf (70 vs. 45%). Während jahrelang das ANV als möglicherweise unvermeidbare Komplikation des septischen Multiorganversagens hingenommen und für die Prognose als nicht wegweisend eingeschätzt wurde, zeigen verschiedene Untersuchungen der letzten Jahre einen unabhängigen, fundamentalen Einfluss des ANV auf das Überleben der Patienten.

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  1. Klinik für Nieren- und Hochdruckkrankheiten am Klinikum Braunschweig, Salzdahlumer Straße 90, 38126, Braunschweig, Germany

    Prof. Dr. Horst P. Kierdorf

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  1. Einheit für Multidisziplinäre Intensivmedizin (EMI), Universitätsklinikum Leipzig AÖR, Liebigstr. 20, 04104, Leipzig

    Lothar Engelmann

  2. Klinikum Hildesheim, Weinberg 1, 31134, Hildesheim

    Hans-Peter Schuster

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Kierdorf, H.P. (2006). Sepsis und Akutes Nierenversagen. In: Engelmann, L., Schuster, HP. (eds) Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen. Steinkopff. https://doi.org/10.1007/978-3-7985-1729-5_10

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