Single ventricle


Single ventricle (or univentricular heart) is considered a congenital cardiac malformation in which both atria connect to only one ventricular chamber by either two separate atrioventricular valves (double inlet) or a common atrioventricular valve (common inlet). The ventricle to which both atrioventricular valves or a common atrioventricular valve connects is generally well formed, whereas the ventricle not receiving the largest amount of the venous return to the heart is often a rudimentary chamber.


Ventricular Septal Defect Single Ventricle Atrioventricular Valve Fontan Procedure Pulmonary Artery Banding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Almond CSD, Mayer JE, Thiagarajan RR, Blume ED, del Nido PJ, McElhinney DB (2007) Outcome after Fontan failure and takedown to an intermediate palliative circulation. Ann Thorac Surg 84:880–887PubMedCrossRefGoogle Scholar
  2. Babu-Narayan SV, Gatzoulis MA, Kilner PJ (2007) Noninvasive imaging in adult congenital heart disease using cardiovascular magnetic resonance. J Cardiovasc Med 8:23–29Google Scholar
  3. Be’eri E, Maier SE, Landzberg MJ, Chung T, Geva T (1998) In vivo evaluation of Fontan pathway flow dynamics by multidimensional phase-velocity magnetic resonance imaging. Circulation 98:2873–2882PubMedGoogle Scholar
  4. Brown DW, Gauvreau K, Powell AJ, Lang P, Colan SD, del Nido PJ, Odegard KC, Geva T (2007) Cardiac magnetic resonance versus routine cardiac catheterization before bidirectional Glenn anastomosis in infants with functional single ventricle. Circulation 116:2718–2725PubMedCrossRefGoogle Scholar
  5. Casolo G, Rega L, Gensini GF (2004) Detection of right atrial and pulmonary artery thrombosis after the Fontan procedure by magnetic resonance imaging. Heart 90:825PubMedCrossRefGoogle Scholar
  6. Choi BW, Park YH, Lee JK, Kim DJ, Kim MJ, Choe KO (2003) Patency of cavopulmonary connection studied by single phase electron beam computed tomography. Int J Cardiovasc Imaging 19:447–455PubMedCrossRefGoogle Scholar
  7. Corno AF, Becker AE, Bulterijs AHK, Lam J, Nijveld A, Schuller C, Marcelletti C (1982) Univentricular heart: can we alter the natural history? Ann Thorac Surg 34:716–726PubMedGoogle Scholar
  8. Corno AF (1996) Considerations on the cavopulmonary connection. Am Coll Cardiol Curr J Rev 5:38Google Scholar
  9. Corno AF, Bonnet D, Sekarski N, Sidi D, Vouhe PR, von Segesser LK(2003) Remote control of pulmonary blood flow: initial clinical experience. J Thorac Cardiovasc Surg 126:1775–1780PubMedCrossRefGoogle Scholar
  10. Corno AF, Horisberger J, Jegger D, von Segesser LK (2004) Right atrial surgery with unsnared inferior vena cava. Eur J Cardiothorac Surg 26:219–220PubMedCrossRefGoogle Scholar
  11. DiSessa TG, Child JS, Perloff JK, Wu L, Williams RG, Laks H, Friedman WF (1984) Systemic venous and pulmonary arterial flow patterns after Fontan’s procedure for tricuspid atresia or single ventricle. Circulation 70:898PubMedGoogle Scholar
  12. Dos L, Pen V, Silversides C, Provost Y, Oechslin E, Horlick E, Paul N (2007) Images in cardiovascular medicine. Cardiac magnetic resonance imaging and multidetector computed tomography scan illustrating Damus-Kaye-Stansel operation. Circulation 115: e440–e442PubMedCrossRefGoogle Scholar
  13. Eichen A, Fratz S, Gutfried C, Balling G, Schwaiger M, Lange R, Busch R, Hess J, Stern H (2003) Hearts late after Fontan operation have normal mass, normal volume, and reduced systolic function: a magnetic resonance imaging study. J Am Coll Cardiol 42:1061–1065CrossRefGoogle Scholar
  14. Festa P, Ait-Ali L, Bernabei M, De Marchi D (2005) The role of magnetic resonance imaging in the evaluation of the functionally single ventricle before and after conversion to the Fontan circulation. Cardiol Young 15(Suppl 3):51–56PubMedCrossRefGoogle Scholar
  15. Fogel MA, Weinberg PM, Fellows KE, Hoffman EA (1993) Magnetic resonance imaging of constant total heart volume and center of mass in patients with functional single ventricle before and after staged Fontan procedure. Am J Cardiol 72:1435–1443PubMedCrossRefGoogle Scholar
  16. Fogel MA, Gupta KB, Weinberg PM, Hoffman EA (1995) Regional wall motion and strain analysis across stages of Fontan reconstruction by magnetic resonance imaging. Am J Physiol 269:H1132–1152PubMedGoogle Scholar
  17. Fogel MA, Weinberg PM, Chin AJ, Fellows KE, Hoffman EA (1996) Late ventricular geometry and performance changes of functional single ventricle throughout staged Fontan reconstruction assessed by magnetic resonance imaging. J Am Coll Cardiol 28:212–221PubMedCrossRefGoogle Scholar
  18. Fogel MA, Weinberg PM, Rychik J, Hubbard A, Jacobs M, Spray TL, Haselgrove J (1999) Caval. Caval contribution to flow in the branch pulmonary arteries of Fontan patients with a novel application of magnetic resonance presaturation pulse. Circulation 99:1215–1221PubMedGoogle Scholar
  19. Fogel MA, Durning S, Wernovsky G, Pollock AN, Gaynor JW, Nicolson S (2004) Brain versus lung: hierarchy of feedback loops in single-ventricle patients with superior cavopulmonary connection. Circulation 110(Suppl II):47–52Google Scholar
  20. Fogel MA (2005) Is routine cardiac catheterization necessary in the management of patients with single ventricles across staged Fontan reconstruction? No! Pediatr Cardiol 26:154–158CrossRefGoogle Scholar
  21. Fogel MA (2006) Cardiac magnetic resonance of single ventricles. J Cardiovasc Magn Reson 8:661–670PubMedCrossRefGoogle Scholar
  22. Frakes DH, Smith MJ, Parks J, Sharma S, Fogel SM, Yoganathan AP (2005) New techniques for the reconstruction of complex vascular anatomies from MRI images. J Cardiovasc Magn Reson 7:425–432PubMedCrossRefGoogle Scholar
  23. Fratz S, Hess J, Schwaiger M, Martinoff S, Stern HC (2002) More accurate quantification of pulmonary blood flow by magnetic resonance imaging than by lung perfusion scintigraphy in patients with Fontan circulation. Circulation 106:1510–1513PubMedCrossRefGoogle Scholar
  24. Garg R, Powell AJ, Sena L, Marshall AC, Geva T (2005) Effects of metallic implants on magnetic resonance imaging evaluation of Fontan palliation. Am J Cardiol 95:688–691PubMedCrossRefGoogle Scholar
  25. Giannico S, Hammad F, Amodeo A, Michielon G, Drago F, Turchetta A, di Donato R, Sanders SP (2006) Clinical outcome of 193 extracardiac Fontan patients. J Am Coll Cardiol 47:2065–2073PubMedCrossRefGoogle Scholar
  26. Goo HW, Yang DH, Park IS, Ko JK, Kim YH, Seo DM, Yun TJ, Park JJ (2007) Time-resolved three-dimensional contrast-enhanced magnetic resonance angiography in patients who have undergone a Fontan operation or bidirectional cavopulmonary connection: initial experience. J Magn Reson Imaging 25: 727–736PubMedCrossRefGoogle Scholar
  27. Greenberg SB, Morrow WR, Imamura M, Drummond-Webb J (2004) Magnetic resonance flow analysis of classic and extracardiac Fontan procedures: the seesaw sign. Int J Cardiovasc Imaging 20:397–405PubMedCrossRefGoogle Scholar
  28. Hayabuchi Y, Mori K, Kitagawa T, Sakata M, Kagami S (2007) Polytetrafluoroethylene graft calcification in patients with surgically repaired congenital heart disease: evaluation using multidetector-row computed tomography. Am Heart J 153:806.e1–808CrossRefGoogle Scholar
  29. Hjortdal VE, Emmertsen K, Stenbog E, Frund T, Schmidt MR, Kromann O, Sorensen K, Pedersen EM (2003) Effects of exercise and respiration on blood flow in total cavopulmonary connection: a real-time magnetic resonance flow study. Circulation 108: 1227–1231PubMedCrossRefGoogle Scholar
  30. Kiesewetter CH, Sheron N, Vettukattil JJ, Hacking N, Stedman B, Millward-Sadler H, Haw M, Cope R, Salmon AP, Sivaprakasam MC, Kendall T, Keeton BR, Iredale JP, Veldtman GR (2007) Hepatic changes in the failing Fontan circulation. Heart 93:579–584PubMedCrossRefGoogle Scholar
  31. Klimes K, Abdul-Khaliq H, Ovroutski S, Hui W, Alexi-Meskishvili V, Spors B, Hetzer R, Felix R, Lange PE, Berger F, Gutberlet M (2007) Pulmonary and caval blood flow patterns in patients with intracardiac and extracardiac Fontan: a magnetic resonance study. Clin Res Cardiol 96:160–167PubMedCrossRefGoogle Scholar
  32. Lilje C, Habermann CR, Weil J (2005) Magnetic resonance imaging follow-up ot total cavopulmonary connection. Heart 91:395PubMedCrossRefGoogle Scholar
  33. Marcelletti C, Corno AF, Giannico S, Marino B (1990) Inferior vena cava to pulmonary artery extracardiac conduit: a new form of right heart bypass. J Thorac Cardiovasc Surg 100:228–232PubMedGoogle Scholar
  34. Mazzera E, Corno AF, Picardo S, Di Donato RM, Marino B, Costa D, Marcelletti C (1989) Bidirectional cavopulmonary shunts: clinical applications as staged or definitive palliation. Ann Thorac Surg 47:415–420PubMedCrossRefGoogle Scholar
  35. Morgan VL, Graham TP, Roselli RJ, Lorenz CH (1998) Alterations in pulmonary artery flow patterns and shear stress determined with three-dimensional phase-contrast magnetic resonance imaging in Fontan patients. J Thorac Cardiovasc Surg 116:294–304PubMedCrossRefGoogle Scholar
  36. Pedersen EM, Stenbog EV, Frund T, Houlind K, Kromann O, Sorensen KE, Emmertsen K, Hjortdal VE (2002) Flow during exercise in the total cavopulmonary connection measured by magnetic resonance velocity mapping. Heart 87:554–558Google Scholar
  37. Rebergen SA, Ottenkamp J, Doornbos J, van der Wall EE, Chin JG, de Roos A (1993) Postoperative pulmonary flow dynamics after Fontan surgery: assessment with nuclear magnetic resonance velocity mapping. J Am Coll Cardiol 21:123–131PubMedGoogle Scholar
  38. Robbers-Visser D, ten Harkel D, Strengers JLM (2007) Cardiac MRI combined with low-dose dobutamine stress reveals an abnormal stress response in children and young adults after Fontan operation at young age. J Cardiovasc Magn Reson 9:107Google Scholar
  39. Socci L, Gervaso F, Migliavacca F, Pennati G, Dubini G, Ait-Ali L, Festa P, Amoretti F, Scebba L, Luisi VS (2005) Computational fluid dynamics in a model of the total cavopulmonary connection reconstructed using magnetic resonance images. Cardiol Young 15 (Suppl 3):61–67PubMedCrossRefGoogle Scholar
  40. Sundareswaran KS, Kanter KR, Kitajima HD, Krishnankutty R, Sabatier JF, Parks WJ, Sharma S, Yoganathan AP, Fogel M (2006) Impaired power output and cardiac index with hypoplastic left heart syndrome: a magnetic resonance imaging study. Ann Thorac Surg 82:1267–1275PubMedCrossRefGoogle Scholar
  41. Weiss F, Habermann CR, Lilje C, Sasse K, Kuhne T, Weil J, Adam G (2002) MRI in postoperative assessment of univentricular heart disease: correlation with echocardiography and angiography. Rofo 174: 1537–1543PubMedGoogle Scholar

Copyright information

© Steinkopff Verlag 2009

Personalised recommendations