Complete transposition of the great arteries


Transposition of the great arteries is an abnormality of ventriculoarterial connection, with the aorta originating from the morphologically right ventricle and the pulmonary artery from the morphologically left ventricle. The aorta is anterior and slightly to the right of the main pulmonary artery. The aortic valve is to the right of the pulmonary valve but still anterior to it. The main pulmonary artery is in a position, with respect to the left ventricle, such that there is direct flow into the right pulmonary artery; as a consequence the right pulmonary artery becomes larger, with more flow to the right lung.


Ventricular Septal Defect Main Pulmonary Artery Great Artery Arterial Switch Operation Ventricular Outflow Tract Obstruction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Babu-Narayan SV, Goktekin O, Moon JC, Broberg CS, Pantely GA, Pennell DJ, Gatzoulis MA, Kilner PJ (2005) Late gadolinium enhancement cardiovascular magnetic resonance of the systemic right ventricle in adults with previous atrial redirection surgery for transposition of the great arteries. Circulation 111: 2091–2098PubMedCrossRefGoogle Scholar
  2. Bex JP, Lecompte Y, Baillot F, Hazan E (1980) Anatomical correction of transposition of the great arteries. Ann Thorac Surg 29:86–88PubMedGoogle Scholar
  3. Choi BW, Park YH, Choi JY, Choi BI, Kim MJ, Ryu SJ, Lee JK, Sul JH, Lee SK, Cho BK, Choe KO (2001) Using electron beam CT to evaluate conotruncal anomalies in pediatric and adult patients. Am J Roentgenol 177:1045–1049Google Scholar
  4. Cook SC, McCarthy M, Daniels CJ, Cheatham JP, Raman SV (2004) Usefulness of multislice computed tomography angiography to evaluate intravascular stents and transcatheter occlusion devices in patients with d-transposition of the great arteries after Mustard repair. Am J Cardiol 94:967–969PubMedCrossRefGoogle Scholar
  5. Corno AF, Laks H, George B, Williams RG (1987) Use of in situ pericardium for surgical relief of pulmonary venous obstruction following Mustard’s operation. Ann Thorac Surg 43:443–444PubMedCrossRefGoogle Scholar
  6. Corno AF, Parisi F, Marino B, Ballerini L, Marcelletti C (1987) Palliative Mustard operation: an expanded horizon. Eur J Cardiothorac Surg 1:144–147PubMedCrossRefGoogle Scholar
  7. Corno AF, George B, Pearl J, Laks (1989) Surgical options for complex transposition of the great arteries. J Am Coll Cardiol 14:742–749PubMedGoogle Scholar
  8. Corno AF, von Segesser LK (2001) Transposition of great arteries and single coronary artery: a new surgical technique for the arterial switch operation. Swiss Med Wkly 131:47–49PubMedGoogle Scholar
  9. Corno AF, Hurni M, Payot M, Sekarski N, Tozzi P, von Segesser LK (2003) Adequate left ventricular preparation allows for arterial switch despite late referral. Cardiol Young 13:49–52PubMedCrossRefGoogle Scholar
  10. Dorfman AL, Geva T (2006) Magnetic resonance imaging evaluation of congenital heart disease: conotruncal anomalies. J Cardiovasc Magn Reson 8:645–659PubMedCrossRefGoogle Scholar
  11. Dos L, Pen V, Silversides C, Provost Y, Oechslin E, Horlick E, Paul N (2007) Images in cardiovascular medicine. Cardiac magnetic resonance imaging and multidetector computed tomography scan illustrating Damus-Kaye-Stansel operation. Circulation 115: e440–442PubMedCrossRefGoogle Scholar
  12. Fogel MA, Hubbard A, Weinberg PM (2001) A simplified approach for assessment of intracardiac baffles and extracardiac conduits in congenital heart surgery with two-and three-dimensional magnetic resonance imaging. Am Heart J 142:1028–1036PubMedCrossRefGoogle Scholar
  13. Fogel MA, Hubbard A, Weinberg PM(2002) Mid-term follow-up of patients with transposition of the great arteries after atrial inversion operation using twoand three-dimensional magnetic resonance imaging. Pediatr Radiol 32:440–446PubMedCrossRefGoogle Scholar
  14. Fratz S, Hauser M, Bengel FM, Hager A, Kaemmerer H, Schwaiger M, Hess J, Stern HC (2006) Myocardial scars determined by delayed-enhancement magnetic resonance imaging and positron emission tomography are not common in right ventricles with systemic function in long-term follow up. Heart 92: 1673–1677PubMedCrossRefGoogle Scholar
  15. Goo HW, Park IS, Ko JK, Kim YH, Seo DM, Yun TJ, Park JJ, Yoon CH (2003) CT of congenital heart disease: normal anatomy and typical pathologic conditions. Radiographics 23:S147–165PubMedCrossRefGoogle Scholar
  16. Gyarmati G, Simor T, Kadar K, Toth L, Nemeth T, Oprea V, Hartyanszky I (2006) Quantification of right and left ventricular function with magnetic resonance imaging after Senning operation for complete transposition of the great arteries. Orv Hetil 147:171–174PubMedGoogle Scholar
  17. Hornung TS, Anagnostopoulos C, Bhardwaj P, Kilner PJ, Davlouros PA, Bailey J, Francis JM, Pennell DJ, Underwood SR, Gatzoulis MA (2003) Comparison of equilibrium radionuclide ventriculography with cardiovascular magnetic resonance for assessing the systemic right ventricle after Mustard or Senning procedures for complete transposition of the great arteries. Am J Cardiol 92:640–643PubMedCrossRefGoogle Scholar
  18. Kiaffas MG, Davlouros P, Tsertos F, Andreou J, Danias PG (2005) Cardiovascular magnetic resonance evaluation of patients with transposition of the great arteries following atrial switch surgical correction. Hellenic J Cardiol 46:69–73PubMedGoogle Scholar
  19. Laffon E, Latrabe V, Jimanez M, Ducassou D, Laurent F, Marthan R (2006) Quantitative MRI comparison of pulmonary hemodynamics in Mustard/Senningrepaired patients suffering from transposition of the great arteries and healthy volunteers at rest.Eur Radiol 16:1442–1448PubMedCrossRefGoogle Scholar
  20. Lecompte Y, Zannini L, Hazan E, Jarreau MM, Bex JP, Tu TV, Neveux JY (1981) Anatomic correction of transposition of the great arteries. J Thorac Cardiovasc Surg 82:629PubMedGoogle Scholar
  21. Lecompte Y, Bex JP (1985) Repair of transposition of the great arteries with ventricular septal defect and left ventricular outflow tract obstruction. J Thorac Cardiovasc Surg 90:151–154PubMedGoogle Scholar
  22. Lissin LW, Li W, Murphy DJ, Hornung T, Swan L, Mullen M, Kilner P, Gatzoulis MA (2004) Comparison of thansthoracic echocardiography versus cardiovascular magnetic resonance imaging for the assessment of ventricular function in adults after atrial switch procedures for complete transposition of the great arteries. Am J Cardiol 93:654–657PubMedCrossRefGoogle Scholar
  23. Livolsi A, Kastler B, Willard D (1989) Pre-and post-operative study of neonatal transposition of the great vessels by magnetic resonance imaging. Ann Cardiol Angiol 38:261–264Google Scholar
  24. Lorenz CH, Walker ES, Graham TP, Powers TA (1995) Right ventricular performance and mass by use of cine MRI late after atrial repair of transposition of the great arteries. Circulation 92(Suppl-II):233–239Google Scholar
  25. Morell VO, Wearden PD (2007) Aortic translocation for the management of transposition of the great arteries with a ventricular septal defect, pulmonary stenosis, and hypoplasia of the right ventricle. Eur J Cardiothorac Surg 31:552–554PubMedCrossRefGoogle Scholar
  26. Oosterhof T, Tulevski II, Roest AA, Stendijk P, Vliegen HW, van der Wall EE, de Roos A, Tijssen JG, Mulder BJ (2005) Disparity between dobutamine stress and physical exercise magnetic resonance imaging in patients with an intra-atrial correction for transposition of the great arteries. J Cardiovasc Magn Reson 7:383–389PubMedCrossRefGoogle Scholar
  27. Ou P, Mousseaux E, Azarine A, Dupont P, Agnoletti G, Vouhé P, Bonnet D (2006) Detection of coronary complications after the arterial switch operation for transposition of the great arteries: first experience with multislice computed tomography in children. J Thorac Cardiovasc Surg 131:639–643PubMedCrossRefGoogle Scholar
  28. Pettersen E, Helle-Valle T, Edvardsen T, Lindberg H, Smith HJ, Smevik B, Smiseth OA, Andersen K (2007) Contraction pattern of the systemic right ventricle. Shift from longitudinal to circumferential shortening and absent global ventricular torsion. J Am Coll Cardiol 49:2450–2456PubMedCrossRefGoogle Scholar
  29. Raisky O, Bergoend E, Agnoletti G, Ou P, Bonnet D, Sidi D, Vouhé PR (2007) Late coronary artery lesions after neonatal arterial switch operation: results of surgical coronary revascularization. Eur J Cardiothorac Surg 31:894–898PubMedCrossRefGoogle Scholar
  30. Raman SV, Cook SC, McCarthy B, Ferketich AK (2005) Usefulness of multidetector row computed tomography to quantify right ventricular size and function in adults with either tetralogy of Fallot or transposition of the great arteries. Am J Cardiol 95:683–686PubMedCrossRefGoogle Scholar
  31. Salehian O, Schwerzmann M, Merchant N, Webb GD, Siu SC, Therrien J (2004) Assessment of systemic right ventricular function in patients with transposition of the great arteries using the myocardial performance index: comparison with cardiac magnetic resonance imaging. Circulation 110:3229–3233PubMedCrossRefGoogle Scholar
  32. Sodian R, Weber S, Markert M, Rassoulian D, Kaczmarek I, Lueth TC, Reichart B, Daebritz S (2007) Stereolithographic models for surgical planning in congenital heart surgery. Ann Thorac Surg 83:1854–1857PubMedCrossRefGoogle Scholar
  33. Sørensen TS, Mosegaard J, Greil GF, Miller S, Seeger A, Hansen OK, Sieverding L (2007) Images in cardiovascular medicine. Virtual cardiotomy for preoperative planning. Circulation 115:e312PubMedCrossRefGoogle Scholar
  34. Tang T, Chiu IS, Chen HC, Cheng KY, Chen SJ (2001) Comparison of pulmonary arterial flow phenomena in spiral and Lecompte models by computational fluid dynamics. J Thorac Cardiovasc Surg 122:529–534PubMedCrossRefGoogle Scholar
  35. Taylor AM, Dymarkowski S, Hamaekers P, Razavi R, Gewillig M, Mertens L, Bogaert J (2005) MR coronary angiography and late-enhancement myocardial MR in children who underwent arterial switch surgery for transposition of great arteries. Radiology 234:542–547PubMedCrossRefGoogle Scholar
  36. Tops LF, Roest AA, Lamb HJ, Vliegen HW, Helbing WA, van der Wall EE, de Roos A (2005) Intraatrial repair of transposition of the great arteries: use of MR imaging after exercise to evaluate regional systemic right ventricular function. Radiology 237:861–867PubMedCrossRefGoogle Scholar
  37. Tulevski II, van der Wall EE, Groenink M, Dodge-Khatami A, Hirsch A, Stoker J, Mulder BJ (2002) Usefulness of magnetic resonance imaging dobutamine stress in asymptomatic and minimally symptomatic patients with decreased cardiac reserve from congenital heart disease (complete and corrected transposition of the great arteries and subpulmonic obstruction). Am J Cardiol 89:1077–1081PubMedCrossRefGoogle Scholar
  38. Yeh T, Ramaciotti C, Leonard SR, Roy L, Nikaidoh H (2007) The aortic translocation (Nikaidoh) procedure: midterm results superior to the Rastelli procedure. J Thorac Cardiovasc Surg 133:461–469PubMedCrossRefGoogle Scholar

Copyright information

© Steinkopff Verlag 2009

Personalised recommendations