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Identification of Rules for Brain Metastases and Survival Time Prediction for Small Cell Lung Cancer Patients

  • Kwei Aryeetey
  • Wojciech Ziarko
  • Patricia Tai
  • Casely Ago
Conference paper
Part of the Advances in Intelligent and Soft Computing book series (AINSC, volume 10)

Abstract

This paper presents experiments with the application of rough set-based data mining methodology to discover predictive rules in small cell lung cancer patient data. The specific prediction targets are the occurrence of the spread of cancer to the brain and the prediction of patient survival time. The obtained results have been derived from patient data supplied by cancer researchers from the Allan Blair Cancer Center, Regina, Saskatchewan, Canada who also provided all the necessary background information and conducted medical evaluation of the results.

Keywords

Brain Metastasis Small Cell Lung Cancer Decision Table Biological Effective Dose Prophylactic Cranial Irradiation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Pawlak, Z. (1991) Rough Sets: Theoretical Aspects of Reasoning About Data, Kluver Academic Publishers, Dordrecht.MATHGoogle Scholar
  2. 2.
    Grzymala-Busse, J. Goodwin L. (1997) Predicting Preterm Birth Risk Using Machine Learning from Data with Missing Values, Bulletin of International Rough Set Society, Vol. 1, No. 1, 17–21.Google Scholar
  3. 3.
    Cheshenchuk, S. Ziarko, W. (1999) Mining Patient Data for Predictive Rules to Determine Maturity Status of Newborn Children, Bulletin of International Rough Set Society, Vol. 3, No 1–2, 23–26.Google Scholar
  4. 4.
    Slowinski, K. Sharif E. (1994) Rough Sets Approach to Analysis of Data of Diagnostic Peritoneal Lavage Applied for Multiple Injuries Patients. In Ziarko, W. ed. Rough Sets, Fuzzy Sets and Knowledge Discover,Springer Verlag, 420–425.Google Scholar
  5. 5.
    Slowinski, K. (1992) Rough Classification of HSV Patients. In Slowinski, R. ed. Intelligent Decision Support,Kluwer Academic Publishers, 77–94.Google Scholar
  6. 6.
    Grace I. Paterson (1994) Rough Classification of Pneumonia Patients Using a Clinical Database. In Ziarko, W. ed. Rough Sets, Fuzzy Sets and Knowledge Discover,Springer Verlag, 412–419.Google Scholar
  7. 7.
    Tsumoto, S. (1999) Discovery of rules about complications. In Proc. of the 7th International Workshop on Rough Sets, Fuzzy Sets, Data Mining and Granular-Soft Computing, Lecture Notes in Artificial Intelligence 1711,Springer—Verlag, 29–37.Google Scholar
  8. 8.
    Tsumoto, S. (1998) Extraction of expert’s decision rules from clinical databases using rough set model,J. Intelligent data Analysis 2(3).Google Scholar
  9. 9.
    Tsumoto, S. (1998) Automated induction of medical expert system rules from clinical databases based on rough set theory, Information Sciences 112, 67–84.CrossRefGoogle Scholar
  10. 10.
    Tsumoto, S. Ziarko, W. (1996) The application of rough sets-based data mining technique to differential diagnosis of meningoencephaliti. Proc. of the Int. Conference on Methodologies for Intelligent Systems, Lecture Notes in Artificial Intelligence, vol. 1079,Springer Verlag, 438–447.Google Scholar
  11. 11.
    Ziarko, W. (1993) Variable precision rough sets model, Journal of Computer and Systems Sciences, vol. 46, no. 1, 39–59.MathSciNetMATHCrossRefGoogle Scholar
  12. 12.
    Rosen S. T., Makuch R. W., Lichter A. S., et al. (1983) Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer. Potential benefit resyticted to patients with complete response, Am. J. Med 74: 615–624.Google Scholar
  13. 13.
    Cox DR. (1972) Regression models and life-tables,J. R. Stat. Soc. B 34: 187–220.MATHGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Kwei Aryeetey
    • 1
  • Wojciech Ziarko
    • 1
  • Patricia Tai
    • 2
  • Casely Ago
    • 2
  1. 1.Computer Science Department University of ReginaReginaCanada
  2. 2.Allan Blair Cancer CenterReginaCanada

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