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Estimation for the Semiparametric Transformation Model under General Censorship

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Aspects of Mathematical Modelling

Part of the book series: Mathematics and Biosciences in Interaction ((MBI))

Abstract

In a semiparametric transformation model, an increasing transformation of the survival time is linearly related to a covariate Z with an error distribution ε — i.e., the survival time T has the property that α (T) = −θ z +ε given Z = z, where α is an unknown extended real-valued function on ℝ and θ is an unknown constant in ℝd. In this paper, we consider the estimation of the transformation function α and the regression coefficient θ when the survival time data are subjected to general censorship. An observation is said to be censored by a general censorship scheme if there are random intervals which would hide the observation when it falls inside them. In such cases, we see the censoring interval instead of the actual observation. The maximum likelihood method is used to estimate the unknown parameters, and the asymptotic properties of the estimators are studied.

Results in this paper were presented at the International Conference on Mathematical Modelling and Computation held at Universiti Brunei Darussalam during 5-8 June 2006. in conjunction with the 20th anniversary of the foundation of the university.

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References

  1. Bennett, S. (1983). Analysis of survival data by the proportional odds model. Statistics in Medicine 2, 273–277.

    Article  Google Scholar 

  2. Cai, T. and Cheng, S. (2004). Semiparametric regression analysis for doubly censored data. Biometrika 91, 277–290.

    Article  MATH  MathSciNet  Google Scholar 

  3. Chang, M. N. and Yang, G. L. (1987). Strong consistency of a nonparametric estimator of the survival function with doubly censored data. Ann. Statist. 15, 1536–1547.

    Article  MATH  MathSciNet  Google Scholar 

  4. Chang, M. N. (1990). Weak convergence of a self-consistent estimator of the survival function with doubly censored data. Ann. Statist. 18, 391–404.

    Article  MATH  MathSciNet  Google Scholar 

  5. Cheng, Y.-C. (2002). Estimation in semiparametric transformation models with doubly censored data. Ph.D. thesis, Department of Statistics, Rutgers University.

    Google Scholar 

  6. Cosslett, S. R. (2004). Efficient semiparametric estimation of censored and truncated regressions via a smoothed self-consistency equation. Econometrica. 72, 1277–1293.

    Article  MATH  MathSciNet  Google Scholar 

  7. Cox, D. R. (1972). Regression models and life tables (with discussion). J. Roy. Statist. Soc. Ser. B 34, 187–220.

    MATH  MathSciNet  Google Scholar 

  8. Dabrowska, D. M. and Doksum, K.A. (1988). Partial likelihood in transformation models with censored data. Scand. J. Statist. 5, 1–23.

    MathSciNet  Google Scholar 

  9. Gehan, E. A. (1965). A generalized two-sample Wilcoxon test for doubly censored data. Biometrika 52 650–653.

    MATH  MathSciNet  Google Scholar 

  10. Geskus, R. B. and Groeneboom, P. (1996). Asymptotically optimal estimation of smooth functionals for interval censoring. I. Statist. Neerlandica 50, 69–88.

    Article  MATH  MathSciNet  Google Scholar 

  11. Gørgens, T. (2003). Semiparametric estimation of censored transformation models. J. Nonparametr. Statist 15, 377–393.

    Article  MATH  Google Scholar 

  12. Gørgens, T. and Horowitz, J.L. (1999). Semiparametric estimation of a censored regression model with an unknown transformation of the dependent variable. J. Econometrics 90, 155–191.

    Article  MathSciNet  Google Scholar 

  13. Groeneboom P. and Wellner, J.A. (1992). Information bounds and nonparametric maximum likelihood estimation. DMV Seminar, 19. Birkhäuser Verlag, Basel.

    Google Scholar 

  14. Gu, M. G. and Zhang, C.-H. (1993). Asymptotic properties of self-consistent estimators based on doubly censored data. Ann. Statist. 21, 611–624.

    Article  MATH  MathSciNet  Google Scholar 

  15. Horowitz, J.L. (1996). Semiparametric estimation of a regression model with an unknown transformation of the dependent variable. Econometrica 64, 103–137.

    Article  MATH  MathSciNet  Google Scholar 

  16. Huang, J. (1996) Efficient estimation for the proportional hazards model with interval censoring. Ann. Statist. 24, 540–568.

    Article  MATH  MathSciNet  Google Scholar 

  17. Jammalamadaka, S. Rao and Mangalam, V. (2003). Nonparametric estimation for middle censored data. J. Nonparametr. Statist. 15, 253–265.

    Article  MATH  MathSciNet  Google Scholar 

  18. Kaplan, E. L. and Meier, P. (1958). Nonparametric estimation from incomplete observations. J. Amer. Statist. Assoc. 53, 457–481.

    Article  MATH  MathSciNet  Google Scholar 

  19. Kim, J. S. (2003). Maximum likelihood estimation for the proportional hazards model with partly interval-censored data. J. Roy. Statist. Soc. Ser. B 65, 489–502.

    Article  MATH  Google Scholar 

  20. Lawless, J.F. (1982). Statistical models and methods for lifetime data. John Wiley & Sons, New York.

    MATH  Google Scholar 

  21. Murphy, S. A., Rossini, A. J and Van Der Vaart, A. W. (1997). Maximum likelihood estimation in the proportional odds model. J. Am. Statist. Assoc. 92, 968–976.

    Article  MATH  Google Scholar 

  22. Pettitt, A.N. (1984). Proportional odds model for survival data and estimates using ranks. Applied Statistics 33, 169–175.

    Article  Google Scholar 

  23. Shen, X. (1998). Proportional odds regression and sieve maximum likelihood estimation. Biometrika 85, 165–177.

    Article  MATH  MathSciNet  Google Scholar 

  24. Turnbull, B.W. (1974). Nonparametric estimation of a survivorship function with doubly censored data. J. Amer. Statist. Assoc. 69, 169–173.

    Article  MATH  MathSciNet  Google Scholar 

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Kumphon, B., Mangalam, V. (2008). Estimation for the Semiparametric Transformation Model under General Censorship. In: Hosking, R.J., Venturino, E. (eds) Aspects of Mathematical Modelling. Mathematics and Biosciences in Interaction. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8591-0_17

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