Natural history and prognosis

  • Dennis Nowak
Part of the Progress in Inflammation Research book series (PIR)


In patients with occupational asthma, the rate of symptomatic recovery after avoidance of exposure to the respective agents is only about one third, worsening with increasing age. Likewise, persistent nonspecific bronchial hyperresponsiveness at long-term follow-up is found in about three quarters of these patients. The situation is even worse if patients with occupational asthma are left in the same workplace. These clinical and functional data are supported by investigations demonstrating inflammation and airway remodeling in the course of occupational asthma despite inhaled steroid medication. Given the frequently adverse outcome of occupational asthma, much more effort should be taken to avoid the disease.


Respir Crit Airway Remodel Occupational Asthma Occupational Rhinitis Fatal Asthma 
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Copyright information

© Birkhäuser / Springer Basel 2010

Authors and Affiliations

  • Dennis Nowak
    • 1
  1. 1.Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Clinical CentreLudwig Maximilian UniversityMünchenGermany

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