The immune response to influenza A viruses

  • Justine D. Mintern
  • Carole Guillonneau
  • Stephen J. Turner
  • Peter C. Doherty
Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)


The influenza A viruses are dangerous pathogens with the potential to provoke devastating disease. The challenge for the medical research community is to design preventive measures and therapeutic interventions that will limit the severe consequences of pandemic influenza A virus infections. Vaccines have long been available, but there is considerable scope for improvement as they target only the prevailing influenza A virus strains, do not give broad immunity and work poorly in the elderly, the target group that is most at risk of fatal disease. Improved vaccines will only emerge if the development strategy is based on a firm understanding of the host immune response to the virus. Here, we summarize the research to date that details immune mechanisms participating in the control and elimination of influenza A viruses.


Influenza Virus Virus Specific Versus IRUS HETEROSUBTYPIC Immunity RECE PTOR 


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Copyright information

© Birkhäuser Verlag Basel/Switzerland 2008

Authors and Affiliations

  • Justine D. Mintern
    • 1
  • Carole Guillonneau
    • 1
  • Stephen J. Turner
    • 1
    • 2
  • Peter C. Doherty
    • 1
    • 2
  1. 1.Department of Microbiology and ImmunologyUniversity of MelbourneParkvilleAustralia
  2. 2.Department of ImmunologySt Jude Children’s Research HospitalMemphisUSA

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