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Dendritic cells and angiogenesis

  • Chapter
Book cover Angiogenesis in Inflammation: Mechanisms and Clinical Correlates

Part of the book series: Progress in Inflammation Research ((PIR))

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Abstract

Dendritic cells (DC) are professional antigen-presenting cells with a unique ability in inducing T and B cell response as well as immune tolerance [1, 2]. DC reside in an immature state in peripheral tissues where they exert a sentinel function for incoming antigens. Upon microbial contact and stimulation by inflammatory cytokines, DC uptake antigens, undergo a process of maturation, and traffic via the afferent lymphatics into the T cell area of the draining lymph node to initiate immune responses [3, 4].

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References

  1. Banchereau, J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K (2000) Immunobiology of dendritic cells. Annu Rev Immunol 18: 767–811

    Article  PubMed  CAS  Google Scholar 

  2. Steinman RM (2003) Some interfaces of dendritic cell biology. APMIS 111: 675–697

    Article  PubMed  CAS  Google Scholar 

  3. Sozzani, S (2005) Dendritic cell trafficking: More than just chemokines. Cytokine Growth Factor Rev 16: 581–592

    Article  PubMed  CAS  Google Scholar 

  4. Sallusto F, Lanzavecchia A (1999) Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J Exp Med 189: 611–614

    Article  PubMed  CAS  Google Scholar 

  5. Shortman K, Liu YJ (2002) Mouse and human dendritic cell subtypes. Nat Rev Immunol 2: 151–161

    Article  PubMed  CAS  Google Scholar 

  6. Barchet WM, Cella M, Colonna M (2005) Plasmacytoid dendritic cells — Virus experts of innate immunity. Semin Immunol 17: 253–261

    Article  PubMed  CAS  Google Scholar 

  7. Dzionek AA, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, Buck DW, Schmitz J (2000) BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 165: 6037–6046

    PubMed  CAS  Google Scholar 

  8. Janeway CA Jr, Medzhitov R (2002) Innate immune recognition. Annu Rev Immunol 20: 197–216

    Article  PubMed  CAS  Google Scholar 

  9. Moser M, Murphy KM (2000) Dendritic cell regulation of TH1–TH2 development. Nat Immunol 1: 199–205

    Article  PubMed  CAS  Google Scholar 

  10. Mahnke K, Enk AH (2005) Dendritic cells: Key cells for the induction of regulatory T cells? Curr Top Microbiol Immunol 293: 133–150

    Article  PubMed  CAS  Google Scholar 

  11. Vulcano M, Dusi S, Lissandrini D, Badolato R, Mazzi P, Riboldi E, Borroni E, Calleri A, Donini M, Plebani A et al (2004) Toll receptor-mediated regulation of NADPH oxidase in human dendritic cells. J Immunol 173: 5749–5756

    PubMed  CAS  Google Scholar 

  12. Vermi W, Facchetti F, Riboldi E, Heine H, Scutera S, Stornello S, Ravarino D, Cappello P, Giovarelli M, Badolato M et al (2006) Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma. Blood 107: 454460

    Article  Google Scholar 

  13. Riboldi E, Musso T, Moroni E, Urbinati C, Bernasconi S, Rusnati M, Adorini L, Presta M, Sozzani S (2005) Cutting edge: Proangiogenic properties of alternatively activated dendritic cells. J Immunol 175: 2788–2792

    PubMed  CAS  Google Scholar 

  14. Zhang M, Tang H, Guo Z, An H, Zhu X, Song W, Guo J, Huang X, Chen T, Wang J, Cao X (2004) Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat Immunol 5: 1124–1133

    Article  PubMed  CAS  Google Scholar 

  15. Webster B, Ekland EH, Agle LM, Chyou S, Ruggieri R, Lu TT (2006) Regulation of lymph node vascular growth by dendritic cells. J Exp Med 203: 1903–1913

    Article  PubMed  CAS  Google Scholar 

  16. Goerdt S, Orfanos CE (1999) Other functions, other genes: Alternative activation of antigen-presenting cells. Immunity 10: 137–142

    Article  PubMed  CAS  Google Scholar 

  17. Mantovani AS, Sozzani S, Locati M, Schioppa T, Saccani A, Allavena P, Sica A (2004) Infiltration of tumours by macrophages and dendritic cells: Tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Novartis Found Symp 256: 137–145

    Article  PubMed  Google Scholar 

  18. Verhasselt V, Buelens C, Willems F, De Groote D, Haeffner-Cavaillon N, Goldman M (1997) Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: Evidence for a soluble CD 14-dependent pathway. J Immunol 158: 2919–2925

    PubMed  CAS  Google Scholar 

  19. de Saint-Vis B, Fugier-Vivier I, Massacrier C, Gaillard C, Vanbervliet B, Ait-Yahia S, Banchereau J, Liu YJ, Lebecque S, Caux C (1998) The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation. J Immunol 160: 1666–1676

    PubMed  Google Scholar 

  20. Trinchieri G (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3: 133–146

    Article  PubMed  CAS  Google Scholar 

  21. Stoll S, Jonuleit H, Schmitt E, Muller G, Yamauchi H, Kurimoto M, Knop J, Enk AH (1998) Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development. Eur J Immunol 28: 3231–3239

    Article  PubMed  CAS  Google Scholar 

  22. Mantovani A, Sozzani S (2000) Chemokines. In: F Balkwill (ed): The cytokine network. Oxford University Press, Oxford, 103–125

    Google Scholar 

  23. Strieter RM, Burdick MD, Mestas J, Gomperts B, Keane MP, Belperio JA (2006) Cancer CXC chemokine networks and tumour angiogenesis. Eur J Cancer 42: 768–778

    Article  PubMed  CAS  Google Scholar 

  24. Caux C, Massacrier C, Vanbervliet B, Dubois B, Van Kooten C, Durand I, Banchereau J (1994) Activation of human dendritic cells through CD40 cross-linking. J Exp Med 180: 1263–1272

    Article  PubMed  CAS  Google Scholar 

  25. Padovan E, Spagnoli GC, Ferrantini M, Heberer M (2002) IFN-alpha2a induces IP-10/CXCL10 and MIG/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells. J Leukoc Biol 71: 669–676

    PubMed  CAS  Google Scholar 

  26. Means TK, Hayashi F, Smith KD, Aderem A, Luster AD (2003) The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. J Immunol 170: 5165–5175

    PubMed  CAS  Google Scholar 

  27. Vicari AP, Ait-Yahia S, Chemin K, Mueller A, Zlotnik A, Caux C (2000) Antitumor effects of the mouse chemokine 6Ckine/SLC through angiostatic and immunological mechanisms. J Immunol 165: 1992–2000

    PubMed  CAS  Google Scholar 

  28. Dubois B, Massacrier C, Caux C (2001) Selective attraction of naive and memory B cells by dendritic cells. J Leukoc Biol 70: 633–641

    PubMed  CAS  Google Scholar 

  29. Doyen V, Rubio M, Braun D, Nakajima T, Abe J, Saito H, Delespesse G, Sarfati M (2003) Thrombospondin 1 is an autocrine negative regulator of human dendritic cell activation. J Exp Med 198: 1277–1283

    Article  PubMed  CAS  Google Scholar 

  30. Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH (2006) Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer. J Immunol 177: 1460–1469

    PubMed  CAS  Google Scholar 

  31. Mainou-Fowler T, Angus B, Miller S, Proctor SJ, Taylor PR, Wood KM (2006) Micro-vessel density and the expression of vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor (PdEGF) in classical Hodgkin lymphoma (HL). Leuk Lymphoma 47: 223–230

    Article  PubMed  CAS  Google Scholar 

  32. Fiallo P, Clapasson A, Favre A, Pesce C (2002) Overexpression of vascular endothelial growth factor and its endothelial cell receptor KDR in type 1 leprosy reaction. Am J Trop Med Hyg 66: 180–185

    PubMed  CAS  Google Scholar 

  33. Liu YJ (2005) IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 23:275–306

    Article  PubMed  CAS  Google Scholar 

  34. Brassard DL, Grace MJ, Bordens RW (2002) Interferon-alpha as an immunotherapeutic protein. J Leukoc Biol 71: 565–581

    PubMed  CAS  Google Scholar 

  35. Penna G, Vulcano M, Roncari A, Facchetti F, Sozzani S, Adorini L (2002) Cutting edge: Differential chemokine production by myeloid and plasmacytoid dendritic cells. J Immunol 169: 6673–6676

    PubMed  CAS  Google Scholar 

  36. Curiel TJ, Cheng P, Mottram P, Alvarez X, Moons L, Evdemon-Hogan M, Wei S, Zou L, Kryczek I, Hoyle G et al (2004) Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer. Cancer Res 64: 5535–5538

    Article  PubMed  CAS  Google Scholar 

  37. Hoehn GT, Stokland T, Amin S, Ramirez M, Hawkins AL, Griffin CA, Small D, Civin CI (1996) Tnk1: A novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin−/CD38− stem/progenitor cells. Oncogene 12: 903–913

    PubMed  CAS  Google Scholar 

  38. Gabrilovich DI, Chen HL, Girgis KR, Cunningham HT, Meny GM, Nadaf S, Kavanaugh D, Carbone DP (1996) Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2: 1096–1103

    Article  PubMed  CAS  Google Scholar 

  39. Casella I, Feccia T, Chelucci C, Samoggia P, Castelli G, Guerriero R, Parolini I, Petrucci E, Pelosi E, Morsilli O et al (2003) Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor. Blood 101: 1316–1323

    Article  PubMed  CAS  Google Scholar 

  40. Katoh O, Tauchi H, Kawaishi K, Kimura A, Satow Y (1995) Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res 55: 5687–5692

    PubMed  CAS  Google Scholar 

  41. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, Oz MC, Hicklin DJ, Witte L, Moore MA, Rafii S (2000) Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 95: 952–958

    PubMed  CAS  Google Scholar 

  42. Clauss M, Weich H, Breier G, Knies U, Rockl W, Waltenberger J, Risau W (1996) The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 271: 17629–17634

    Article  PubMed  CAS  Google Scholar 

  43. Fernandez Pujol B, Lucibello FC, Zuzarte M, Lutjens P, Muller R, Havemann K (2001) Dendritic cells derived from peripheral monocytes express endothelial markers and in the presence of angiogenic growth factors differentiate into endothelial-like cells. Eur J Cell Biol 80: 99–110

    Article  PubMed  CAS  Google Scholar 

  44. Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D (1996) Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87: 3336–3343

    PubMed  CAS  Google Scholar 

  45. Hamrah, P, Chen L, Zhang Q, Dana MR (2003) Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells. Am J Pathol 163: 57–68

    PubMed  CAS  Google Scholar 

  46. Chen L, Hamrah P, Cursiefen C, Zhang Q, Pytowski B, Streilein JW, Dana MR (2004) Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. Nat Med 10: 813–815

    Article  PubMed  CAS  Google Scholar 

  47. Dzionek A, Inagaki Y, Okawa K, Nagafune J, Rock J, Sohma Y, Winkels G, Zysk M, Yamaguchi Y, Schmitz J (2002) Plasmacytoid dendritic cells: From specific surface markers to specific cellular functions. Hum Immunol 63: 1133–1148

    Article  PubMed  CAS  Google Scholar 

  48. Tordjman R, Lepelletier Y, Lemarchandel V, Cambot M, Gaulard P, Hermine O, Romeo PH (2002) A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response. Nat Immunol 3: 477–482

    PubMed  CAS  Google Scholar 

  49. Young MR (2006) Cytokine-containing gelfoam implants at a postsurgical tumor excision site to stimulate local immune reactivity. Int J Cancer 119: 133–138

    Article  PubMed  CAS  Google Scholar 

  50. Young MR, Cigal M (2006) Tumor skewing of CD34+ cell differentiation from a dendritic cell pathway into endothelial cells. Cancer Immunol Immunother 55: 558–568

    Article  PubMed  Google Scholar 

  51. Staquet MJ, Godefroy S, Jacquet C, Viac J, Schmitt D (2001) Vascular endothelial growth factor (VEGF) induces human Langerhans cell migration. Arch Dermatol Res 293: 26–28

    Article  PubMed  CAS  Google Scholar 

  52. Oyama TS, Ran S, Ishida T, Nadaf S, Kerr L, Carbone DP, Gabrilovich DI (1998) Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells. J Immunol 160: 1224–1232

    PubMed  CAS  Google Scholar 

  53. Laxmanan S, Robertson SW, Wang E, Lau JS, Briscoe DM, Mukhopadhyaya D (2005) Vascular endothelial growth factor impairs the functional ability of dendritic cells through Id pathways. Biochem Biophys Res Commun 334: 193–198

    Article  PubMed  CAS  Google Scholar 

  54. Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP (2005) Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J Immunol 174: 215–222

    PubMed  CAS  Google Scholar 

  55. Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP (1999) Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res 5: 2963–2970

    PubMed  CAS  Google Scholar 

  56. Lee CG, Link H, Baluk P, Homer RJ, Chapoval S, Bhandari V, Kang MJ, Cohn L, Kim YK, McDonald DM, Elias JA (2004) Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 10: 1095–1103

    Article  PubMed  CAS  Google Scholar 

  57. Rutella S, Danese S, Leone G (2006) Tolerogenic dendritic cells: Cytokine modulation comes of age. Blood 108: 1435–1440

    Article  PubMed  CAS  Google Scholar 

  58. Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA (2006) Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 24: 99–146

    Article  PubMed  CAS  Google Scholar 

  59. Borkowski TA, Letterio JJ, Farr AG, Udey MC (1996) A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: The skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells. J Exp Med 184: 2417–2422

    Article  PubMed  CAS  Google Scholar 

  60. Geissmann F, Revy P, Regnault A, Lepelletier Y, Dy M, Brousse N, Amigorena S, Hermine O, Durandy A (1999) TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells. J Immunol 162: 4567–4575

    PubMed  CAS  Google Scholar 

  61. Rutella S, Bonanno G, Procoli A, Mariotti A, de Ritis DG, Curti A, Danese S, Pessina G, Pandolfi S, Natoni F et al (2006) Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin, (IL)-10++IL-12low/neg accessory cells with dendritic-cell features. Blood 108: 218–227

    Article  PubMed  CAS  Google Scholar 

  62. Kawamura K, Iyonaga K, Ichiyasu H, Nagano J, Suga M, Sasaki Y (2005) Differentiation, maturation, and survival of dendritic cells by osteopontin regulation. Clin Diagn Lab Immunol 12: 206–212

    Article  PubMed  CAS  Google Scholar 

  63. Guruli G, Pflug BR, Pecher S, Makarenkova V, Shurin MR, Nelson JB (2004) Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops. Blood 104: 2107–2115

    Article  PubMed  CAS  Google Scholar 

  64. Leali D, DelľEra P, Stabile H, Sennino B, Chambers AF, Naldini A, Sozzani S, Nico B, Ribatti D, Presta M (2003) Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis. J Immunol 171: 1085–1093

    PubMed  CAS  Google Scholar 

  65. Weiss JM, Renkl AC, Maier CS, Kimmig M, Liaw L, Ahrens T, Kon S, Maeda M, Hotta H, Uede T, Simon JC (2001) Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med 194: 1219–1229

    Article  PubMed  CAS  Google Scholar 

  66. Renkl AC, Wussler J, Ahrens T, Thoma K, Kon S, Uede T, martin SF, Simon JC, Weiss JM (2005) Osteopontin functionally activates dendritic cells and induces their differentiation towards a Th1-polarizing phenotype. Blood 106: 946–955

    Article  PubMed  CAS  Google Scholar 

  67. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H (2000) Eta-1 (osteopontin): An early component of type-1 (cell-mediated) immunity. Science 287: 860–864

    Article  PubMed  CAS  Google Scholar 

  68. Abel B, Freigang S, Bachmann MF, Boschert U Kopf M (2005) Osteopontin is not required for the development of Th1 responses and viral immunity. J Immunol 175: 6006–6013

    PubMed  CAS  Google Scholar 

  69. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H (2006) Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol 7: 498–506

    Article  PubMed  CAS  Google Scholar 

  70. Marteau F, Gonzalez NS, Communi D, Goldman M, Boeynaems JM (2005) Thrombospondin-1 and indoleamine 2,3-dioxygenase are major targets of extracellular ATP in human dendritic cells. Blood 106: 3860–3866

    Article  PubMed  CAS  Google Scholar 

  71. Demeure CE, Tanaka H, Mateo V, Rubio M, Delespesse G, Sarfati M (2000) CD47 engagement inhibits cytokine production and maturation of human dendritic cells. J Immunol 164: 2193–2199

    PubMed  CAS  Google Scholar 

  72. Xia CQ, Kao KJ (2003) Effect of CXC chemokine platelet factor 4 on differentiation and function of monocyte-derived dendritic cells. Int Immunol 15: 1007–1015

    Article  PubMed  CAS  Google Scholar 

  73. Fricke I, Mitchell D, Petersen F, Bohle A, Bulfone-Paus S, Brandau S (2004) Platelet factor 4 in conjunction with IL-4 directs differentiation of human monocytes into specialized antigen-presenting cells. FASEB J 18: 1588–1590

    PubMed  CAS  Google Scholar 

  74. Ribatti D, Vacca A, Nico B, Crivellato E, De Falco G, Presta M (2003) Cross talk between haematopoiesis and angiogenesis. Adv Exp Med Biol 522: 25–36

    PubMed  CAS  Google Scholar 

  75. Choi K, Kennedy M, Kazarov A, Papadimitriou JC, Keller G (1998) A common precursor for hematopoietic and endothelial cells. Development 125: 725–732

    PubMed  CAS  Google Scholar 

  76. Choi J, Enis DR, Koh KP, Shiao SL, Pober JS (2004) T lymphocyte-endothelial cell interactions. Annu Rev Immunol 22: 683–709

    Article  PubMed  CAS  Google Scholar 

  77. Harraz M, Jiao C, Hanlon HD, Hartley RS, Schatteman GC (2001) CD34− blood-derived human endothelial cell progenitors. Stem Cells 19: 304–312

    Article  PubMed  CAS  Google Scholar 

  78. Conejo-Garcia JR, Benencia F, Courreges MC, Kang E, Mohamed-Hadley A, Buckanovich RJ, Holtz DO, Jenkins A, Na H, Zhang L et al (2004) Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of VEGF-A. Nat Med 10: 950–958

    Article  PubMed  CAS  Google Scholar 

  79. Conejo-Garcia JR, Buckanovich RJ, Benencia F, Courreges MC, Rubin SC, Carroll RG, Coukos G (2005) Vascular leukocytes contribute to tumor vascularization. Blood 105: 679–681

    Article  PubMed  CAS  Google Scholar 

  80. Coukos G, Tenencia F, Buckanovich RJ, Conejo-Garcia JR (2005) The role of dendritic cell precursors in tumour vasculogenesis. Br J Cancer 92: 1182–1187

    Article  PubMed  CAS  Google Scholar 

  81. Hendrix MJ, Seftor EA, Hess AR, Seftor RE (2003) Vasculogenic mimicry and tumour-cell plasticity: Lessons from melanoma. Nat Rev Cancer 3: 411–421

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, University of Brescia, Viale Europa 11, 25123, Brescia, Italy

    Elena Riboldi, Silvano Sozzani & Marco Presta

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  1. Elena Riboldi
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  2. Silvano Sozzani
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  3. Marco Presta
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Editors and Affiliations

  1. Centre for Experimental Medicine and Rheumatology William Harvey Research Institute, St. Bartholomew’s Hospital, Charterhouse Square, London, E1M 6BQ, UK

    Michael P. Seed

  2. Academic Rheumatology, University of Nottingham, Clinical Sciences Building City Hospital Hucknall Road, Nottingham, NG5 1PB, UK

    David A. Walsh

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Riboldi, E., Sozzani, S., Presta, M. (2008). Dendritic cells and angiogenesis. In: Seed, M.P., Walsh, D.A. (eds) Angiogenesis in Inflammation: Mechanisms and Clinical Correlates. Progress in Inflammation Research. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-7650-5_3

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