Detection of respiratory bacterial pathogens

  • Reinhard Marre
Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)


Microbiology of community-acquired pneumonia often is based on indirect or precarious evidence. Time and effort to detect a respiratory pathogen often is not sufficiently related to its usefulness in guiding therapy. If sputa are accepted by the laboratory for microbiological studies (Gram stain, culture), they should fulfill quality criteria such as high number of leukocytes and low number of squamous epithelial cells. Complementary tests such as antigen detection assays are useful adjuncts for diagnosing pneumococcal and Legionella pneumonia. Nucleic amplification tests help to overcome the problems in detecting Chlamydia pneumoniae, Legionella and Mycoplasma pneumoniae.


Sputum Sample Mycoplasma Pneumoniae Sputum Culture Pneumococcal Pneumonia Legionnaire Disease 
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Copyright information

© Birkhäuser Verlag Basel/Switzerland 2007

Authors and Affiliations

  • Reinhard Marre
    • 1
  1. 1.University of UlmInstitute of Medical Microbiology & HygieneGermany

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