Poxviruses pp 47-64 | Cite as

Genus Orthopoxvirus: Variola virus

  • Inger K. Damon
Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)


Variola major virus caused the human disease smallpox; interpretations of the historic record indicate that the initial introduction of disease in a naïve population had profound effects on its demographics. Smallpox was declared eradicated by the World Health Organization (WHO) in 1980. This chapter reviews epidemiological, clinical and pathophysiological observations of disease, and review some of the more recent observations on the microbiology of Variola virus


Vaccinia Virus Case Fatality Rate Variola Virus Bull World Health Organ Cowpox Virus 
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© Birkhäuser Verlag Basel/Switzerland 2007

Authors and Affiliations

  • Inger K. Damon
    • 1
  1. 1.Poxvirus Program, Division of Viral and Rickettsial DiseasesCenters for Disease Control and PreventionAtlantaUSA

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