Current challenges and approaches for the synergistic use of systems biology data in the scientific community

  • Christian H. Ahrens
  • Ulrich Wagner
  • Hubert K. Rehrauer
  • Can Türker
  • Ralph Schlapbach
Part of the Experientia Supplementum book series (EXS, volume 97)


Today’s rapid development and broad application of high-throughput analytical technologies are transforming biological research and provide an amount of data and analytical opportunities to understand the fundamentals of biological processes undreamt of in past years. To fully exploit the potential of the large amount of data, scientists must be able to understand and interpret the information in an integrative manner. While the sheer data volume and heterogeneity of technical platforms within each discipline already poses a significant challenge, the heterogeneity of platforms and data formats across disciplines makes the integrative management, analysis, and interpretation of data a significantly more difficult task. This challenge thus lies at the heart of systems biology, which aims at a quantitative understanding of biological systems to the extent that systemic features can be predicted. In this chapter, we discuss several key issues that need to be addressed in order to put an integrated systems biology data analysis and mining within reach.


Gene Expression Omnibus System Biology Markup Language Protein Interaction Data Open Biomedical Ontology Gene Expression Database 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag/Switzerland 2007

Authors and Affiliations

  • Christian H. Ahrens
    • 1
  • Ulrich Wagner
    • 1
  • Hubert K. Rehrauer
    • 1
  • Can Türker
    • 1
  • Ralph Schlapbach
    • 1
  1. 1.Functional Genomics Center ZurichZurichSwitzerland

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