Zusammenfassung
Das Pankreaskarzinom steht an fünfter Stelle der durch Krebs bedingten Todesfälle. Die Ursache hierfür ist eine in der Regel frühe lymphatische, hämatogene und peritoneale Metastasierung, aber auch das Fehlen typischer Frühsymptome, der Mangel an effektiven Screening-Methoden und die schlechte diagnostische Abklärbarkeitdes retroperitoneal gelegenen Organs. Es ist damit um so wichtiger, bei Vorliegen eines klinischen Verdachtes das volle diagnostische und therapeutische Spektrum zu nutzen. Nur so kann der zur Zeit deprimierend niedrige Anteil von kurativ behandelbaren Patienten gesteigert werden.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Klöppel G, Held G, Morohoshi T, et al (1982) Klassifikation exokriner Pankreastumoren, histologische Untersuchungen an 167 autoptischen und 97 bioptischen Fällen. Pathologe 3: 319
Martin FM, Rossi RL, Dorrucci V, et al (1990) Clinical and pathologic correlations in patients with periampullary tumors. Arch Surg 125: 723
Kümmerle F, Rückert K (1978) Chirurgie des endokrinen Pankreas in der Bundesrepublik. Ergebnisse einer Umfrage. DMW 103: 729
Heitz PU, Klöppel G (1986) Endokrine Pankreastumoren. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarziom — frühdiagnostisches und therapeutisches Dilemma. Springer, Berlin Heidelberg New York Tokyo, S 427
de Rooij PD, Rogatko A, Brennan MF (1991) Evaluation of palliative surgical procedures in unresectable pancreatic cancer. Br J Surg 78: 1053
Niederau C, Grendell JH (1992) Diagnosis of pancreatic carcinoma — imaging techniques and tumor markers. Pancreas 7: 66
Bakkevold KE, Arnesjo B, Kambestad B (1992) Carcinoma of the pancreas and papilla of Vater — assessment of resectability and factors influencing resectability in stage I carcinomas. A prospective multicentre trial in 472 patients. Eur J Surg Oncol 18: 494
Yasuda K, Mukai H, Nakajima N, et al (1992) Clinical application of ultrasonic probes in the biliary and pancreatic duct. Endoscopy 24: 370
Aspestrand F, Kolmannskog F (1992) CT compared to angiography for staging of tumors of the pancreatic head. Acta Radiol 33: 556
Garber SJ, Lees WR (1992) The characterization of pancreatic and bile duct tumors by duplex doppler. Clin Rad 45: 181
Tio TL, Tytgat GN (1986) Endoscopic ultrasonography in staging local resectability of pancreatic and periampullary malignancy. Scand J Gastroenterol 21 [Suppl] 123: 135
Strunk H, Kuhn FP, Weibler U, et al (1988) Sonographie beim Pankreaskarzinom. Radiologe 28: 277
Warshaw AL, Tepper JE, Shipley WU (1986) Laparoscopy in the staging and planning of therapy for pancreatic cancer. Am J Surg 151: 76
Warshaw AL (1991) Implications of peritoneal cytology for staging of early pancreatic cancer. Am J Surg 161: 26
Gudjonsson B (1987) Cancer of the pancreas: 50 years of surgery. Cancer 60: 2284
Manabe T, Ohshio G, Baba N, et al (1989) Radical pancreatectomy for ductal cell carcinoma of the head of the pancreas. Cancer 64: 1132
Fortner JG (1981) Surgical principles for pancreatic cancer: regional total and subtotal pancreatectomy. Cancer 47: 1712
Warshaw AL, Swanson RS (1988) Pancreatic cancer in 1988. Ann Surg 208: 541
Fortner JG (1989) Radical abdominal cancer surgery: current state and future course. Jpn J Surg 19: 503
Fortner JG (1984) Regional Pancreatectomy for cancer of the pancreas, ampulla, and other related sites. Ann Surg 199: 418
Siridelar WF (1989) Clinical experience with regional pancreatectomy for adenocarcinoma of the pancreas. Arch Surg 124: 127
Dresler CM, Fortner JG, McDermott K, et al (1991) Metabolic consequences of (regional) total pancreatectomy. Ann Surg 214: 131
Grace PA, Pitt HA, Tompkins RK, et al (1986) Decreased morbidity and mortality after pancreatoduodenectomy. Am J Surg 151: 141
Crist DW, Sitzman JV, Cameron JL (1987) Improved hospital morbidity, mortality and survival after the Whipple procedure. Ann Surg 206: 358
Klöppel G, Lohse T, Bosslet K, et al (1987) Ductal adenocarcinoma of the head of the pancreas: incidence of tumor involvement beyond the Whipple resection line. Histological and immunocytochemical analysis of 37 total pancreatectomy specimens. Pancreas 2: 1 70
Edis AJ, Kiernan PD, Taylor WF (1980) Attempted curative resection or ductal carcinoma or the pancreas — review of the Mayo Clinic experience, 1951–1975. Mayo Clin Proc 55: 531
Connolly MM, Dawson PJ, Michelassi F, et al (1987) Survival in 1001 patients with carcinoma of the pancreas. Ann Surg 206: 366 (abstr)
The Gastrointestinal Tumor Study Group (1987) Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 59: 2006
Rappaport MD, Villalba M (1990) A comparison of cholecysto- and choledochoenterostomy for obstructing pancreatic cancer. Am Surg 56: 433
Singh SM, Longmire WPJ, Reber HA (1990) Surgical palliation for pancreatic cancer. The UCLA experience. Ann Surg 212: 132
Mosdell DM, Kessler C, Morris DM (1991) Unresectable pancreatic cancer: what is the optimal procedure? South Med J 84: 571
Cotton PB (1989) Nonsurgical palliation of jaundice in pancreatic cancer. Surg Clin North Am 69: 613
Sharfman WH, Walsh TD (1990) Has the analgesic efficacy of neurolytic celiac plexus block been demonstrated in pancreatic cancer pain? Pain 41: 267
The Gastrointestinal Tumor Study Group, Kaiser MH, Ellenberg SS (1985) Pancreatic cancer: adjuvant combined radiation and chemotherapy following curative resection. Arch Surg 120: 899
Whittington R, Bryer MP, Haller DG, et al (1991) Adjuvant therapy of resected adenocarcinoma of the pancreas. Int J Radiat Oncol Biol Phys 21: 1137
Trede M, Schwall G, Saeger HD (1990) Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 211: 447
Nagakawa T, Konishi I, Ueno K, et al (1991) The results and problems of extensive radical surgery for carcinoma of the head of the pancreas. Jpn J Surg 21: 262
Sindelar WF, Kinsella TJ (1986) Randomized trial of intraoperative and external beam radiotherapy in unresectable carcinoma of the pancreas. Int J Rad Oncol Biol Phys 12: 148
Tepper JE, Noyes D, Krall JM, et al (1991) Intraoperative radiation therapy of pancreatic carcinoma: a report of RTOG-8505. Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 21: 1145
Griffin JF, Smalley SR, Jewell W, et al (1990) Patterns of failure after curative resection of pancreatic carcinoma. Cancer 66: 56
Bittner R, Roscher R, Safi F, et al (1989) Die Auswirkung von Tumordurchmesser und Lymphknotenstatus auf die Prognose des Pankreaskarzinoms. Chirurg 60: 240
Tsuchiya R, Tomioka T, Izawa K, et al (1986) Collective review of small carcinomas of the pancreas. Ann Surg 203: 77
Manabe T, Miyashita T, Ohshio G, et al (1988) Small carcinoma of the pancreas: clinical and pathological evaluation of 17 patients. Cancer 62: 135
Nix GA, Dubbelman C, Wilson JH, etal (1991) Prognostic implications of tumor diameter in carcinoma of the head of the pancreas. Cancer 67: 529
Mannell A, Weiland LH, Van Heeren JA, etal (1986) Factors influencing survival after resection for ductal adenocarcinoma of the pancreas. Ann Surg 203: 403
Cameron JL, Crist DW, Sitzmann JV, et al (1991) Factors influencing survival after pancreaticoduodenectomy for pancreatic cancer. Am J Surg 161: 120
Nix GA, Dubbelman C, Srivastava ED, etal (1991) Prognostic implications of the localization of carcinoma in the head of the pancreas. Am J Gastroenterol 86: 1027
Willett CG, Warshaw AL, Convery K, etal (1993) Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. Surg Gynecol Obstet 176: 33
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag/Wien
About this paper
Cite this paper
Moesta, K.T., Schlag, P.M. (1995). Pankreaskarzinom. In: Schlag, P.M., Dittrich, C. (eds) Maligne gastrointestinale Tumoren. Angewandte Onkologie. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9417-1_19
Download citation
DOI: https://doi.org/10.1007/978-3-7091-9417-1_19
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82716-1
Online ISBN: 978-3-7091-9417-1
eBook Packages: Springer Book Archive