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Tumour Volume Reduction Following Gamma Knife Radiosurgery: The Relationship Between X-ray and Histological Findings

  • Conference paper
Advances in Radiosurgery

Part of the book series: Acta Neurochirurgica Supplementum ((NEUROCHIRURGICA,volume 62))

Abstract

The case histories of two young ladies with Cushing’s disease are described. Both patients were treated first with Gamma Knife radiosurgery and subsequently by microsurgery. The radiosurgery caused a marked reduction in tumour volume but only a partial relief of the endocrinopathy.

Comparison of the histological findings with the radiological findings following radiosurgery indicates that confluent necrosis is not a prerequisite for a reduction in tumour volume. It seems more likely that the reduction in tumour volume is related to changes in cellular dynamics.

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References

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Haukeland Hospital, University of Bergen, Bergen, N-5027, Norway

    J. C. Ganz M.A., Ph.D., FRCS

  2. Department of Endocrinology, Haukeland Hospital, University of Bergen, Norway

    S. Aanderud

  3. Department of Pathology, Haukeland Hospital, University of Bergen, Norway

    S. J. Mork

  4. Department of Radiology, Haukeland Hospital, University of Bergen, Norway

    A.-I. Smievoll

Authors
  1. J. C. Ganz M.A., Ph.D., FRCS
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  2. S. Aanderud
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  3. S. J. Mork
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  4. A.-I. Smievoll
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Editor information

Editors and Affiliations

  1. Gamma Knife Center, Karolinska Hospital, Stockholm, Sweden

    Christer Lindquist

  2. Department of Neurological Surgery and Radiation Oncology, Presbyterian University Hospital, Pittsburgh, PA, USA

    Douglas Kondziolka

  3. Joint Center of Radiation Therapy, Boston, MA, USA

    Jay S. Loeffler

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© 1994 Springer-Verlag

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Ganz, J.C., Aanderud, S., Mork, S.J., Smievoll, AI. (1994). Tumour Volume Reduction Following Gamma Knife Radiosurgery: The Relationship Between X-ray and Histological Findings. In: Lindquist, C., Kondziolka, D., Loeffler, J.S. (eds) Advances in Radiosurgery. Acta Neurochirurgica Supplementum, vol 62. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9371-6_8

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  • DOI: https://doi.org/10.1007/978-3-7091-9371-6_8

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9373-0

  • Online ISBN: 978-3-7091-9371-6

  • eBook Packages: Springer Book Archive

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