Zusammenfassung
In den letzten Jahren wurden deutliche Fortschritte in der Entwicklung und Anwendung bildgebender Verfahren bei neuropsychiatrischen Krankheitsbildern gemacht [1–3]. Neben den die Hirnstruktur mit hoher räumlicher Auflösung darstellenden Verfahren der Transmissions-Computertomographie und der Magnetresonanz Tomographie wird durch Verfahren wie die Positronen-Emissions-Tomographie (PET) und Einzel-Photonen-Emissions-Tomographie (SPECT) die Darstellung von Funktionsstörungen des Gehirns ermöglicht [2]. Bei zahlreichen neuropsychiatrischen Krankheitsbildern wie auch bei der im Rahmen dieser Darstellung interessierenden Schizophrenie sind morphologisch-strukturelle Veränderungen des Gehirns eher subtil und die Interpretation dieser Veränderungen ist im Einzelfall durch große Überlappungen zu gesunden Kontrollgruppen zusätzlich erschwert. Auch ist nicht zu erwarten, daß sich bei einem schizophrenen Patienten mit akuter psychotischer Symptomatik ein anderer morphologischer Befund zeigt als in der Remissionsphase.
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Broich, K., Kasper, S., Danos, P., Grünwald, F., Laux, G., Möller, HJ. (1994). „Frontale Hypoperfusion“ mittels SPECT bei schizophrener Minussymptomatik. In: Möller, HJ., Laux, G. (eds) Fortschritte in der Diagnostik und Therapie schizophrener Minussymptomatik. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9349-5_14
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