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Natural recombination in bovine viral diarrhea viruses

  • Conference paper
Positive-Strand RNA Viruses

Part of the book series: Archives of Virology Supplementum ((ARCHIVES SUPPL,volume 9))

Summary

BVDV isolates exist as two biotypes differentiated at the molecular level by production of a p80 polypeptide. Insertions consisting of host cell sequences and/or duplicated and rearranged viral sequences have been observed in the portion of the genome coding for the p80 polypeptide in some, but not all, cytopathic BVDV. The significance of these insertions to biotypic expression has yet to be demonstrated. It has been hypothesized that recombination results in the production of the p80 polypeptide by introduction of a cleavage site into a precursor polypeptide or the introduction of a second copy of the p80 gene. Because inserts have not been identified in all cytopathic BVDV examined, it appears that recombination may not be the only mechanism involved in biotypic determination.

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Author information

Authors and Affiliations

  1. Virology Cattle Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa, USA

    Dr. J. F. Ridpath & S. R. Bolin

  2. Department of Veterinary Science, North Dakota State University, Fargo, North Dakota, USA

    F. Qi & E. S. Berry

Authors
  1. Dr. J. F. Ridpath
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  2. F. Qi
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  3. S. R. Bolin
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  4. E. S. Berry
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Editor information

Editors and Affiliations

  1. Department of Biology, Georgia State University, Atlanta, Georgia, USA

    Margo A. Brinton

  2. Arthropod-borne and Infectious Disease Laboratory (AIDL), Colorado State University, Fort Collins, Colorado, USA

    Charles H. Calisher

  3. Institute for Molecular Virology, University of Wisconsin, Madison, Wisconsin, USA

    Roland Rueckert

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© 1994 Springer-Verlag

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Ridpath, J.F., Qi, F., Bolin, S.R., Berry, E.S. (1994). Natural recombination in bovine viral diarrhea viruses. In: Brinton, M.A., Calisher, C.H., Rueckert, R. (eds) Positive-Strand RNA Viruses. Archives of Virology Supplementum, vol 9. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9326-6_24

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  • DOI: https://doi.org/10.1007/978-3-7091-9326-6_24

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82522-8

  • Online ISBN: 978-3-7091-9326-6

  • eBook Packages: Springer Book Archive

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