Skip to main content
SpringerLink
Log in
Book cover

Amine Oxidases: Function and Dysfunction pp 75–81Cite as

The effects of ethanol on rat brain monoamine oxidase activities

  • Conference paper

Part of the book series: Journal of Neural Transmission ((NEURAL SUPPL,volume 41))

Summary

In contrast to the reported behaviour of human platelet MAO-B, chronic ethanol feeding does not significantly affect the sensitivities of either MAO-A or -B from rat brain to inhibition by ethanol in vitro. The thermal stabilities of rat brain MAO-A and -B are not significantly affected by chronic ethanol feeding.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anokhina JP, Kogan BM, Drozdov AZ (1988) Disturbances in regulation of catecholamine neuromediation in alcoholism. Alcohol Alcoholism 23: 343–350.

    CAS  Google Scholar 

  • Carrilho M, Freire A, Ponces Freire A, Amorim M, Alves P, Pinto Correia J (1988) Effects of ethanol consumption on hepatic mitochondrial enzymes. Gastroenterology Int 1 [Suppl] 1: A610.

    Google Scholar 

  • Cloninger CR (1987) Neurogenic adaptive mechanisms in alcoholism. Science 236: 410–416.

    Article  PubMed  CAS  Google Scholar 

  • Fowler CJ, Tipton KF (1982) Deamination of 5-hydroxytryptamine by both forms of monoamine oxidase in the rat brain. J Neurochem 38: 733–736.

    Article  PubMed  CAS  Google Scholar 

  • Fowler CJ, Tipton KF, MacKay AVP, Youdim MBH (1980a) Human platelet monoamine oxidase — a useful enzyme in the study of psychiatric disorders?. Neuroscience 7: 1577–1594.

    Article  Google Scholar 

  • Fowler CJ, Callingham BA, Mantle TJ, Tipton KF (1980b) The effects of lipophilic compounds upon the activity of rat liver mitochondrial monoamine oxidase-A and — B. Biochem Pharmacol 29: 1177–1183.

    Article  PubMed  CAS  Google Scholar 

  • Knorring A-L von, Bohman M, Knorring L von, Oreland L (1985) Platelet monoamine oxidase activity as a biological marker in subgroups of alcoholism. Acta Psychiatr Scand 72: 51–58.

    Article  Google Scholar 

  • Lieber CS, DeCarli LM (1986) The feeding of alcohol in liquid diets. Alcohol Clin Exp Res 6: 523–531.

    Article  Google Scholar 

  • Lieber CS, DeCarli LM (1989) Liquid diet technique of ethanol administration 1989 update. Alcohol Alcoholism 24: 197–211.

    CAS  Google Scholar 

  • Markwell MAK, Haas SM, Bieber LL, Tolbert NE (1978) A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 87: 206–210.

    Article  PubMed  CAS  Google Scholar 

  • Oreland L, Wiberg Å, Winblad B, Fowler CJ, Gottfries G-G, Kiianmaa K (1983) The activity of monoamine oxidase-A and-B in brains from chronic alcoholics. J Neural Transm 56: 73–83.

    Article  PubMed  CAS  Google Scholar 

  • Pandey GN, Fawcett J, Gibbons R, Clark DC, Davis JM (1988) Platelet monoamine oxidase in alcoholism. Biol Psychiatry 24: 15–24.

    Article  PubMed  CAS  Google Scholar 

  • Romanova LA (1980) The effects of acute and chronic administration of ethanol on monoamine oxidase activity in rat brain and liver tissues. Vopr Med Khim Acad Med Nauk SSSR 26: 252–255.

    CAS  Google Scholar 

  • Sullivan H, Baebziger JC, Wagner DL, Rauscher FP, Nurnberger JI, Holmes JS (1990) Platelet MAO subtypes in alcoholism. Biol Psychiatry 27: 911–922.

    Article  PubMed  CAS  Google Scholar 

  • Tabakoff B, Lee JM, De Leon-Jones F, Hoffman PL (1985) Ethanol inhibits the activity of the B form of monoamine oxidase in human platelet and brain tissue. Psychopharmacology 87: 152–156.

    Article  PubMed  CAS  Google Scholar 

  • Tabakoff B, Hoffman PL, Lee JM, Saito T, Willard B, De Leon-Jones JM (1988) N Engl J Med 318: 134–139.

    Article  PubMed  CAS  Google Scholar 

  • Tipton KF (1985) Determination of monoamine oxidase. Meth Find Exp Clin Pharmacol 7: 361–367.

    CAS  Google Scholar 

  • Tipton KF (1988) Central neurotransmission and alcohol: critique. Neurochem Int 13: 301–305.

    Article  PubMed  CAS  Google Scholar 

  • Wiberg Å, Wahlström G, Oreland L (1977) Brain monoamine oxidase activity after chronic ethanol treatment. Psychopharmacology 52: 111–113.

    Article  PubMed  CAS  Google Scholar 

  • Yates WR, Wilcox J, Knudson R, Myers C, Kelly MW (1990) The effects of gender and subtype on platelet MAO in alcoholism. J Stud Alc 51: 463–467.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmacology, University of Florence, Viale G. B. Morgagni 65, I-50134, Florence, Italy

    Prof. Dr. L. Della Corte, L. Bianchi & A. Colivicchi

  2. Department of Biochemistry, Trinity College, Dublin, Ireland

    N. P. Kennedy & K. F. Tipton

Authors
  1. Prof. Dr. L. Della Corte
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Bianchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Colivicchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. P. Kennedy
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. F. Tipton
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Biochemistry Department, Trinity College, Dublin, Ireland

    K. F. Tipton

  2. Department of Pharmacology, Technion, Haifa, Israel

    M. B. H. Youdim

  3. School of Pharmacy and Biomedicai Sciences, University of Portsmouth, UK

    C. J. Barwell

  4. Department of Pharmacology, University of Cambridge, UK

    B. A. Callingham

  5. Department of Pharmacology and Clinical Pharmacology, University of Dundee, UK

    G. A. Lyles

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag

About this paper

Cite this paper

Della Corte, L., Bianchi, L., Colivicchi, A., Kennedy, N.P., Tipton, K.F. (1994). The effects of ethanol on rat brain monoamine oxidase activities. In: Tipton, K.F., Youdim, M.B.H., Barwell, C.J., Callingham, B.A., Lyles, G.A. (eds) Amine Oxidases: Function and Dysfunction. Journal of Neural Transmission, vol 41. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9324-2_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-9324-2_9

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82521-1

  • Online ISBN: 978-3-7091-9324-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation