Summary
In rat mesenteric artery homogenates histamine is oxidatively deaminated at high rate whereas putrescine is a poor substrate. The oxidation of histamine appears to be mainly catalyzed by an SSAO enzyme with high affinity for benzylamine (Bz.SSAO). Histamine oxidation is inhibited by B24 (2,5-diethoxy-4-aminomethylpyridine), a selective inhibitor of Bz.SSAO enzymes, and reduced by the presence of benzylamine.
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© 1994 Springer-Verlag
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Banchelli, G., Ignesti, G., Pirisino, R., Raimondi, L., Buffoni, F. (1994). Histaminase activity of mesenteric artery of the rat. In: Tipton, K.F., Youdim, M.B.H., Barwell, C.J., Callingham, B.A., Lyles, G.A. (eds) Amine Oxidases: Function and Dysfunction. Journal of Neural Transmission, vol 41. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9324-2_60
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DOI: https://doi.org/10.1007/978-3-7091-9324-2_60
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82521-1
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