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Histaminase activity of mesenteric artery of the rat

  • G. Banchelli
  • G. Ignesti
  • R. Pirisino
  • L. Raimondi
  • F. Buffoni
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 41)

Summary

In rat mesenteric artery homogenates histamine is oxidatively deaminated at high rate whereas putrescine is a poor substrate. The oxidation of histamine appears to be mainly catalyzed by an SSAO enzyme with high affinity for benzylamine (Bz.SSAO). Histamine oxidation is inhibited by B24 (2,5-diethoxy-4-aminomethylpyridine), a selective inhibitor of Bz.SSAO enzymes, and reduced by the presence of benzylamine.

Keywords

Mesenteric Artery Amine Oxidase Diamine Oxidase Oxidative Deamination Epididymal White Adipose Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • G. Banchelli
    • 1
  • G. Ignesti
    • 1
  • R. Pirisino
    • 1
  • L. Raimondi
    • 1
  • F. Buffoni
    • 1
  1. 1.Dipartimento di Farmacologia preclinica e clinicaUniversità di FirenzeFirenzeItaly

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