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Semicarbazide-sensitive amine oxidase activity of guinea pig dorsal skin

  • F. Buffoni
  • S. Cambi
  • G. Banchelli
  • G. Ignesti
  • R. Pirisino
  • L. Raimondi
Conference paper
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 41)

Summary

A semicarbazide-sensitive amine oxidase activity with a high affinity for benzylamine (Bz.SSAO) (E.C. 1.4.3.6) is present in guinea pig dorsal skin. This enzymic activity oxidized benzylamine, histamine, 1,4-methylhistamine and acetylputrescine and was inhibited by semicarbazide and by B24 (3,5-diethoxy-4-aminomethylpyridine), a selective inhibitor of Bz.SSAO enzymes. It cross reacted with the antibodies raised against pure pig plasma benzylamine oxidase. Immunohistochemistry showed that it was localized in fibroblasts.

Keywords

Amine Oxidase Dorsal Skin Diamine Oxidase Skin Healing Skin Wound Healing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • F. Buffoni
    • 1
  • S. Cambi
    • 1
  • G. Banchelli
    • 1
  • G. Ignesti
    • 1
  • R. Pirisino
    • 1
  • L. Raimondi
    • 1
  1. 1.Dipartimento di Farmacologia preclinica e clinicaUniversità di FirenzeFirenzeItaly

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