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Identification of human monoamine oxidase (MAO) A and B gene promoters

  • J. C. Shih
  • Q.-S. Zhu
  • J. Grimsby
  • K. Chen
Conference paper
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 41)

Summary

The promoter of human monoamine oxidase (MAO) A and B genes have been identified. The core promoter region of MAO A is comprised of two 90 bp repeats each of which contains two Sp1 elements and lacks a TATA box. The MAO B core promoter region contains two sets of overlapping Spl sites which flank a CACCC element all upstream of a TATA box. The different organization of the MAO A and B promoters may underlie their different cell and tissue specific expression.

Keywords

Promoter Activity Core Promoter Region Potential Transcription Factor Binding Site Decrease Promoter Activity Human Monoamine Oxidase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • J. C. Shih
    • 1
  • Q.-S. Zhu
    • 1
  • J. Grimsby
    • 1
  • K. Chen
    • 1
  1. 1.Department of Molecular Pharmacology and Toxicology, School of PharmacyUniversity of Southern CaliforniaLos AngelesUSA

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