Summary
We give a brief introduction into the chemical relationship between iron and oxidative stress serving two purposes:
Firstly we will mention possible deleterious consequences of iron accumulation in central nervous system (CNS) to biomolecules essential for cell viability. Secondly, we try to discuss some difficulties scientists have to face when interpreting experimental data by which they want to prove or to rule out a role of reactive oxygen species (ROS) in the pathogenesis or progression of human diseases.
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Götz, M.E., Dirr, A., Gsell, W., Burger, R., Freyberger, A., Riederer, P. (1993). Some reflections on iron dependent free radical damage in the central nervous system. In: Riederer, P., Youdim, M.B.H. (eds) Iron in Central Nervous System Disorders. Key Topics in Brain Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9322-8_4
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DOI: https://doi.org/10.1007/978-3-7091-9322-8_4
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82520-4
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