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Alternativen zu Tierversuchen in Ausbildung, Qualitätskontrolle und Herz-Kreislauf-Forschung pp 140–148Cite as

Numerisches Modell zur Simulation der elektrischen Aktivität des menschlichen Herzens

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Part of the book series: Ersatz- und Ergänzungsmethoden zu Tierversuchen ((TIERVERSUCHE))

Zusammenfassung

Der Zweck eines Computermodells ist, bekannte Forschungsergebnisse, die in Form von Meßdaten und Strukturerkenntnissen vorliegen, optimal zu nutzen und ein besseres Verständnis für den Ablauf von komplexen Prozessen zu gewinnen.

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Literatur

  • Arnold L., Page J., Attwell D., Cannell M., Eisner D.A., The dependence on heart rate of human ventricular action potential duration, Cardiovasc. Res., 16, 547–551, 1982.

    Article  PubMed  CAS  Google Scholar 

  • Brembilla-Perrot B., Terrier de la Chaise, A., Cherrier F., Pernot C, Evaluation of the refractory periods of the atrioventricular accessory pathways, Eur. Heart J. 9, Abstract supplement 1, 205 (abstract publication), 1988.

    Google Scholar 

  • Denes P., Wu D., Dhingra R., Pietras R.J., Rosen K.M., The effects of cycle length on cardiac refractory periods in man, Circulation 49, 32–41, 1974.

    Article  PubMed  CAS  Google Scholar 

  • Edvardsson N., Hirsch I., Olsson S.B., Right ventricular monophasic action potentials in healthy young men, PACE 7, 813–821, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Eichtinger Ch., Wach P., Killmann R., Brauer H., Improved forward solution of ECG and MCG mapping derived from a distributed soruce within an integral equation model, Graz: Proceedings BME Austria, 126-130, 1988.

    Google Scholar 

  • Eichtinger Ch., Modellstudien über Magnetokardiographie, Dissertation an der Technischen Universität Graz, 1990.

    Google Scholar 

  • Endresen K., Amlie J.P., Forfang K., Simonsen S., Jensen O., Monophasic action potentials in patients with coronary artery disease: reproducibility and electrical restitution and conduction at different stimulation rates, Cardiovasc. Res. 21, 696–702, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Geselowitz D.B., Miller W.T., A bidomain model for anisotropic cardiac muscle. Ann. Biomed. Eng. 11, 191–206, 1983.

    Article  PubMed  CAS  Google Scholar 

  • Graumann R., Abraham-Fuchs K., Moshage W., Schneiders., Reconstruction of current densities with anatomical constraints, Münster: Proceedings 8th International Conference on Biomagne-tism, 353–354, 1991.

    Google Scholar 

  • Heinecker R., Gonska B.D., EKG in Praxis und Klinik, Stuttgart: Georg Thieme-Verlag, 1992.

    Google Scholar 

  • Heistracher T., Modellierung der Einflüsse der Innervation des Herzens auf die Erregungsausbreitung, Diplomarbeit an der Technischen Universität Graz, 1991.

    Google Scholar 

  • Joannides A.A., Bolton J.P.R., Clake C.J.S., Continuous probabilistic solutions to the bio-magnetic inverse problem, Inverse Problems 6, 523–542, 1990.

    Article  Google Scholar 

  • Killmann R., Three-dimensional numerical simulation of the excitation and repolarisation process in the entire human heart with special emphasis on reentrant tachycardias, Dissertation at Graz University of Technology, 1990.

    Google Scholar 

  • Killmann R., Wach P., Dienstl F., Three-dimensional computer model of the entire human heart for simulation of reentry and tachycardia: gap phenomenon and Wolff-Parkinson-White syndrome, Basic Res. Cardiol. 86, 485–501, 1991a.

    Article  PubMed  CAS  Google Scholar 

  • Killmann R., Wach P., Renhardt M., Rosian M., Mathematische Modellierung der Aktionspotentialformen des Herzens, Biomed. Tech. 36, Ergänzungsband 1, 250–251, 1991b.

    Google Scholar 

  • MacLeod R.S., Percutaneous transluminal coronary angioplasty as a model of cardiac ischemia: clinical and modelling studies, Dissertation, Dalhousie University Halifax, 1990.

    Google Scholar 

  • Meijs J.W.H., Weier O.W., Peters M.J., Oosterom A., On the numerical accuracy of the boundary element method, IEEE Trans. on Biomed. Eng. 36, 1038–1049, 1989.

    Article  CAS  Google Scholar 

  • Miller W.T., Geselowitz D.B., Simulation studies of the electrocardiogram, I. The normal heart, Circ. Res. 43, 301–314, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Moshage W., Achenbach S., Graumann R., Schneider S., Göhl K., Bachmann K., Strom-dichte-Rekonstruktion in der klinischen Magnetokardiographie, Biomed. Tech., 36, Ergänzungsband 1, 147–148, 1991.

    Article  Google Scholar 

  • Myerburg R.J., Gelband H., Castellanos A., Nilsson K., Sung R.J., Bassett A.L., Electro-physiology of endocardial intraventricular conduction: The role and function of the specialized conducting system, in: Wellens H.J.J., Lie K.I., Janse M.J. (eds.), The conduction system of the heart. Structure, function and clinical implications, 2nd ed Martinus Nijhoff Medical Division, The Hague, 336-359, 1978.

    Google Scholar 

  • Omori I., Inoue D., Shirayama T., Asayama J., Katsume H., Nakagawa M., Effect of paced cycle length on sinus node effective refractory period before and after autonomic blockade in patients with sick sinus syndrome, Eur. Heart J. 10, 409–416, 1989.

    PubMed  CAS  Google Scholar 

  • Plonsey R., Quantitative formulations of electrophysiological sources of potential fields in volume conductors, IEEE Transactions on biomedical engineering 31, 868–872, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Renhardt M., Wach P., Killmann R., Modellierung der Kontraktion des Herzens innerhalb eines numerischen Herzmodells, Biomed. Tech. 36, Ergänzungsband 1, 258–259, 1991.

    Article  Google Scholar 

  • Rensma P.L., Maurits M.A., Lammers W.J.E.P., Bonke F.I.M., Schalij M.J., Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs, Circ. Res. 62, 395–410, 1988.

    Article  PubMed  CAS  Google Scholar 

  • Stevenson W.G., Wiener I., Weiss J.N., Effects of spatial separation of stimulation sites on ventricular refractoriness during programmed electrical stimulation, Am. Heart J. 114, 1396–1399, 1987.

    Article  PubMed  CAS  Google Scholar 

  • Wach P., Killmann R., Eichtinger Ch., Schuy S., Ein Vergleich der Auswertung der intramu-ralen und epikardialen bzw. endokardialen Verteilung des Transmembranpotentials zur Darstellung der Quellstruktur im EKG-und MKG-Vorwärtsproblem, Biomed. Tech. 33, 261–265, 1988.

    Article  CAS  Google Scholar 

  • Wach P., Killmann R., Dienstl F., Eichtinger Ch., A computer model of human ventricular myocardium for simulation of ECG, MCG and activation sequence including reentry rhythms, Basic Res. Cardiol. 84, 404–413, 1989.

    Article  PubMed  CAS  Google Scholar 

  • Wiener K., Kunkes S., Rubin D., Kupersmith K., Packer M., Pitchon R., Schwietzer P., Effects of sudden change in cycle length on human atrial, atrioventricular nodal and ventricular refractory periods, Circulation 64, 245–248, 1981.

    Article  PubMed  CAS  Google Scholar 

  • Wohlfart B., A simple model for demonstration of STT-changes in ECG, Eur. Heart J. 8, 409–416, 1987.

    PubMed  CAS  Google Scholar 

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Authors
  1. P. Wach
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  2. R. Killmann
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  3. F. Dienstl
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  4. M. Renhardt
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  5. P. Fleischmann
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Editor information

Editors and Affiliations

  1. Institut für Medizinische Physik und Biophysik, Graz, Österreich

    Harald Schöffl , H. Spielmann  & B. Koidl ,  & 

  2. Tierforschungsanlage der Universität Konstanz, Deutschland

    F.-P. Gruber

  3. SIAT — Schweizer Institut für Alternativen zu Tierversuchen, Zürich, Schweiz

    A. Reinhardt

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© 1993 Springer-Verlag Wien

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Cite this paper

Wach, P., Killmann, R., Dienstl, F., Renhardt, M., Fleischmann, P. (1993). Numerisches Modell zur Simulation der elektrischen Aktivität des menschlichen Herzens. In: Schöffl, H., Spielmann, H., Koidl, B., Gruber, FP., Reinhardt, A. (eds) Alternativen zu Tierversuchen in Ausbildung, Qualitätskontrolle und Herz-Kreislauf-Forschung. Ersatz- und Ergänzungsmethoden zu Tierversuchen. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9307-5_23

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  • DOI: https://doi.org/10.1007/978-3-7091-9307-5_23

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82488-7

  • Online ISBN: 978-3-7091-9307-5

  • eBook Packages: Springer Book Archive

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