Molecular analysis of the human coronavirus (strain 229E) genome

  • J. Herold
  • T. Raabe
  • S. G. Siddell
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 7)


The nucleotide sequence of the human coronavirus strain 229E (HCV 229E) has been determined. This article describes the organization of the virus genome, the predicted viral gene products and the mechanisms which regulate viral gene expression. This information provides a basis to investigate the biology and pathogenesis of HCV.


Mouse Hepatitis Virus Viral Gene Product Human Coronavirus Murine Hepatitis Virus Murine Coronavirus 


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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • J. Herold
    • 1
  • T. Raabe
    • 1
  • S. G. Siddell
    • 1
    • 2
  1. 1.Institute of VirologyUniversity of WürzburgWürzburgFederal Republic of Germany
  2. 2.Institute of VirologyUniversity of WürzburgWürzburgFederal Republic of Germany

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