Establishment of cell lines from bovine brain

Brief Report
  • A. Uysal
  • O.-R. Kaaden
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 7)


As shown by immunocytochemistry, 16 cell lines of neuronal, oligodendroglial or neuronoglial origin have been established from bovine fetal brain by immortalization with SV40 virus and cloning in soft agar. The cell lines were characterized according to their cell surface markers using mono- and polyclonal antibodies.


Soft Agar Bovine Spongiform Encephalopathy Bovine Brain Brain Cell Culture Scrapie Agent 


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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • A. Uysal
    • 1
    • 2
  • O.-R. Kaaden
    • 1
    • 2
  1. 1.Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin,Tierärztliche FakultätLudwig-Maximilians-Universität MünchenMunichFederal Republic of Germany
  2. 2.Institute for Medical Microbiology, Infectious and Epidemic Diseases, Veterinary FacultyLudwig-Maximilians-University MunichMunichFederal Republic of Germany

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