The experience with measles in the United States
Prior to measles vaccine licensure, virtually every child in the United States suffered from measles. While the reported number of cases averaged approximately 525,000 annually, an incidence rate of 315 per 100,000 total population, the actual yearly number of cases approached 4 million [1–4]. Measles vaccine offered the opportunity to prevent this substantial health burden. This report will describe the results achieved using a single dose measles vaccine schedule, recent recommendations for a two-dose schedule, and the efforts to control a resurgence of measles in the United States.
KeywordsMeasle Vaccine Measle Vaccination Immunization Level Vaccine Failure Measle Outbreak
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