Abstract
This chapter describes and discusses the differentiation and quantitation of combined effects with respect to synergism or potentiation on the one hand, and antagonism on the other, in complex interactions. In the combinations considered here, the agents exhibit effects in the same direction, when tested singly. Hence, in binary mixtures, both compounds are active. This is the situation which most researchers associate with the expression of “combined effects”.
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© 1993 Springer-Verlag/Wien
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Pöch, G. (1993). Synergism/potentiation and antagonism — phenomena and mechanisms. In: Combined Effects of Drugs and Toxic Agents. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9276-4_3
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DOI: https://doi.org/10.1007/978-3-7091-9276-4_3
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82434-4
Online ISBN: 978-3-7091-9276-4
eBook Packages: Springer Book Archive