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Experiment MIRGEN

  • H. Tuschl
  • W. Klein
  • R. Kovac
  • E. Ott
  • M. S. Chajdakow
  • Y. J. Voronkov

Abstract

Investigations of the experiment “MIRGEN” were aimed at the evaluation of effects of space flight, like ionising radiation, microgravity or stress, on possible modifications of genetic information. Chemicals, environmental pollution, ionising radiation are known to damage DNA (=deoxyribonucleic acid). Cells normally recognize genetic damage and eliminate modifications within their genetic information by various DNA repair processes. DNA damage not removed by cellular enzymes can lead to impairment of metabolic processes, disturbance in DNA synthesis, cell cycle and differentiation. Late effects of DNA damage may result in tumorigenesis and inherited genetic diseases.

Keywords

Space Flight Sister Chromatid Exchange Sedimentation Profile Sampling Term Mitogen Stimulate Lymphocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1992

Authors and Affiliations

  • H. Tuschl
  • W. Klein
  • R. Kovac
  • E. Ott
  • M. S. Chajdakow
  • Y. J. Voronkov

There are no affiliations available

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