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Bronchial Provocation Testing in Children — Methods and Clinical Relevance

  • Karl F. Kerrebijn
Conference paper

Abstract

Bronchial responsiveness is measured by means of dose-response-curves to bronchoconstricting agents. Bronchial sensitivity is determined by the position of the dose-response-curve. In asthmatics it is shifted to the left. So sensitivity is measured by the position of the curve, a leftward shift is called a hypersensitivity. But that is not the only phenomenon, there is more. Normals and mild asthmatics have a plateau, they have a maximal level of bronchoconstriction. That is very important because a maximal level of bronchoconstriction indicates that airways can only narrow to a certain level. Normals show a plateau at low level, mild asthmatics and COPD-patients show intermediate plateau values, and in severe asthmatics a plateau cannot be measured unless we bring the patient into a danger.

Keywords

Airway Hyperresponsiveness Bronchial Hyperresponsiveness Bronchial Responsiveness Tidal Breathing Pulmonary Resistance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1992

Authors and Affiliations

  • Karl F. Kerrebijn
    • 1
  1. 1.Faculteit der Geneeskunde en GezondheidswetenschappenErasmus UniversiteitRotterdamThe Netherlands

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