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The role of anatomic information in quantifying functional neuroimaging data

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Part of the book series: Journal of Neural Transmission ((NEURAL SUPPL,volume 37))

Summary

When using modern neuroimaging tools, such as CT, PET, SPECT, MRI and MEG, in brain research and brain diagnostics, there is a common need for including external anatomical information into the interpretation and analysis of data. This information may be used to aid the interpretation of structures in images from low resolution imaging tools. With high resolution tools it can help to identify resolved structures. It can also facilitate the merging of data from different modalities, or from different individuals. The anatomical information is often given as regions of interests (ROIs), which may be manually created from an anatomy rich image or automatically created from a standard template collection or from an atlas data base. Automatic methods will lead to a substantial reduction in bias and in size of the systematic errors. Functional ROIs can correspondingly be derived from functional images (usually PET or SPECT). Different aspects of these processes are discussed in the report.

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References

  • Bajcsy R, Lieberson R, Reivich M (1983) A computerized system for the elastic matching of deformed radiographic images to idealized atlas images. J Comput Assist Tomogr 7: 618–625

    Article  PubMed  CAS  Google Scholar 

  • Bohm C, Greitz T, Kingsley D, Berggren BM, Olsson L (1983) Adjustable computerized stereotaxic brain atlas for transmission and emission tomography. Am J Neuroradiol 4: 731–733

    PubMed  CAS  Google Scholar 

  • Bohm C, Greitz T, Berggren BM (1985) Selection of PET ROIs from a computerized brain atlas. J Cereb Blood Flow Metab 5 [Suppl] 1: S613 - S614

    Google Scholar 

  • Bohm C, Greitz T, Blomqvist G, Farde L, Forsgren PO, Kingsley D, Sjögren I, Wiesel FA, Wik G (1986) Applications of a computerized adjustable brain atlas in positron emission tomography. Acta Radiol [Suppl] 369: 449–452

    CAS  Google Scholar 

  • Bohm C, Greitz T, Seitz R, Eriksson L (1991) Specification and selection of regions of interest (ROIs) in a computerized brain atlas. J Cereb Blood Flow Metab 11: A64 - A68

    Article  PubMed  CAS  Google Scholar 

  • Evans AC, Beil C, Marett S, Thompson C, Hakim A (1988) Anatomical-functional correlation using an adjustable MRI-based region of interest atlas with positron emission tomography. J Cereb Blood Flow Metab 8: 513–530

    Article  PubMed  CAS  Google Scholar 

  • Fox PT, Perlmutter JS, Raichle ME (1985) A stereotactic method of localization for positron emission tomography. J Comput Assist Tomogr 9: 141–153

    Article  PubMed  CAS  Google Scholar 

  • Fox PT, Mintun MA, Reinman EM, Raichle ME (1988) Enhanced detection of focal brain responses using intersubject PET images. J Cereb Blood Flow Metab 8: 642–653

    Article  PubMed  CAS  Google Scholar 

  • Friston KJ, Frith CD, Liddle PF, Lammertsma AA, Dolan RD, Frackowiak RSJ (1989) The relationship between local and global changes in PET scan. J Cereb Blood Flow Metab 10: 458–466

    Article  Google Scholar 

  • Friston KJ, Frith CD, Liddle PF, Frackowiak RSJ (1991) Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab 11: 690–699

    Article  PubMed  CAS  Google Scholar 

  • Greitz T, Bohm C, Eriksson L, Mogard J, Roland PE, Seitz RJ, Wiesel FA (1989) The construction of a functional brain atlas: elimination of bias from anatomical variations at PET by reformatting three-dimensional data into a standardized anatomy. In: Ottoson D, Rostene W (eds) Visualization of brain functions. Macmillan, London, pp 137–140 (Wenner-Gren Center International Symposium, vol 53 )

    Google Scholar 

  • Greitz T, Bohm C, Holte S, Eriksson L (1991) A computerized brain atlas: construction, anatomical content, and some applications. J Comput Assist Tomogr 15: 26–38

    Article  PubMed  CAS  Google Scholar 

  • Maguire GQ, Noz ME, Rusinek H, Jaeger J, Kramer EL, Sanger JJ, Smith G (1991) Graphics applied to medical image registration. Comput Graph Appl 2 /2: 20–28

    Article  Google Scholar 

  • Mazziotta JC (1984) Physiologic neuroanatomy. New brain imaging methods present a challenge to an old discipline. J Cereb Blood Flow Metab 4: 481–483

    Article  PubMed  CAS  Google Scholar 

  • Mazziotta JC, Phelps ME, Plummer D, Kuhl DE (1981) Quantitation in positron emission computed tomography. 5. Physical-anatomical effects. J Comput Assist Tomogr 5: 734–743

    Article  PubMed  CAS  Google Scholar 

  • Montgomery DC (1983) Design and analysis of experiments, 2nd edn. Wiley, New York, pp 32–36

    Google Scholar 

  • Seitz RJ, Bohm C, Greitz T, Roland PE, Eriksson L, Blomqvist G, Rosenkvist G, Nordell B (1990) Accuracy and precision of the computerized brain atlas program for localization and quantification in positron emission tomography. J Cereb Blood Flow Metab 10: 443–457

    Article  PubMed  CAS  Google Scholar 

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© 1992 Springer-Verlag

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Bohm, C., Greitz, T., Thurfjell, L. (1992). The role of anatomic information in quantifying functional neuroimaging data. In: Ågren, H., Martinot, JL., Wiesel, FA. (eds) Studies of Brain Metabolism in Psychiatric Patients: Can Standards Be Drawn?. Journal of Neural Transmission, vol 37. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9209-2_6

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  • DOI: https://doi.org/10.1007/978-3-7091-9209-2_6

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82346-0

  • Online ISBN: 978-3-7091-9209-2

  • eBook Packages: Springer Book Archive

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