Zusammenfassung
Der Begriff „Multiorganversagen“ (MOF) wurde erstmals 1977 von Eiseman für das in den späten 60er Jahren beschriebene Krankheitsbild des multiplen, progredienten und/oder sequentiellen Versagens von Organen eingeführt [1]. In den 80er Jahren wurde dieser Begriff durch den des „multiple systems organ failure“ (MSOF) ersetzt [2]. Dieser Terminus erschien in Anbetracht des Versagens der gesamten Homöostase im Rahmen dieses Krankheitsbildes als zutreffender.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Eiseman B, Beart R, Norton L (1977) Multiple organ failure. Surg Gynecol Obstet 144: 323–326
Border JR, Chenier R, McMenamy R (1976) Multiple systems organ failure: muscle fuel deficit with visceral protein malnutrition. Surg Clin North Am 56: 1147–1169
Rush BF, Sori AJ, Murphy TF, Smith S, Flanagan JJ, Machiedo GW (1988) Endotoxemia and bacteremia during hemorrhagic shock. The link between trauma and sepsis? Ann Surg 207: 549–554
Fiddian-Green RG (1988) Splanchnic ischemia and multiple organ failure in the critically ill. Ann R Coll Surg Engl 70: 128–134
Rampp M, Lundgren 0, Nilsson NJ (1968) Extravascular shunting of oxygen in the small intestine of the cat. Acta Physiol Scand 72: 396–403
Hallbäck DA, Hulten L, Jodal M, Lindhagen J, Lundgren O (1978) Evidence for the existence of a countercurrent exchanger in the small intestine in man. Gatroenterology 74: 683–690
Bohlen HG (1980) Intestinal tissue Pot and microvascular responses during glucose exposure. Am J Physiol 238: H164 - H171
Pries AR, Secomb TW, Gaethgens P, Gross JF (1990) Blood flow in microvascular networks. Experiments and simulations. Circ Res 67: 826–834
Jodal M, Lundgren O (1970) Plasma skimming in the intestinal tract. Acta Physiol Scand 80: 50–60
Mela L, Miller LD, Diaco JF, Sugerman HJ (1979) Effect of E. coli endotoxin on mitochondrial energy-linked functions. Surgery 68: 541–549
Cerra FB (1986) Hypermetabolism, organ failure and metabolic support. Surgery 101: 1–13
Falk A, Redfors H, Myrvold H, Haglund U (1985) Small intestinal mucosal lesions in feline septic shock: a study on the pathogenesis. Circ Shock 17: 327–337
Deitch EA (1990) Intestinal permeability is increased in burn patients shortly after injury. Surgery 107: 411–416
Bounous G, McArdle AH, Hodges DM (1966) Biosynthesis of intestinal mucin in shock: relation to tryptic hemorrhagic enteritis and permeability to curare. Ann Surg 164: 13–22
Rhodes RS, DePalma RG, Robinson AV (1973) Intestinal barrier function in hemorrhagic shock. J Surg Res 14: 305–312
Granger DN, Richardson PDI, Kvietys PR, Mortillaro NA (1980) Intestinal blood flow. Gastroenterology 78: 837–863
Hulten L, Lindhagen J, Lundgren O (1977) Sympathetic nervous control of intramural bloodflow in the feline and human intestines. Gastroenterology 72: 41–48
Gershon MD, Erde SM (1981) The nervous system of the gut. Gastroenterology 80: 1571–1594
Taylor KM, Casals JG, Brown JJ (1980) Hemodynamic effects of SQ14225 after cardiopulmonary bypass. Cardiovasc Res 14: 199–205
Bailey RW, Bulkley GB, Hamilton SR, Morris JB (1987) Protection of the small intestine from nonocclusive mesenteric ischemic injury due to cardiogenic shock. Am J Surg 153: 108–116
Collins JD, Bassendine MF, Ferner R (1983) Incidence and prognostic importance of jaundice after cardiopulmonary bypass surgery. Lancet II 1119–1122
Feiner H (1976) Pancreatitis after cardiac surgery. Am J Surg 131: 684–688
Aranha GV, Pickleman J, Pifarre R, Scanlon PJ, Gunnar RM (1984) The reasons for gastrointestinal consultation after cardiac surgery. Am Surg 50: 301–304
Beutler B, Cerami A (1987) Chachektin: more than a tumor necrosis factor. N Engl J Med 317: 653–655
Bevilacqua MP, Pober JS, Majeau GR (1986) Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterisation and comparison with with the actions of interleukin-1. Proc Natl Acad Sci USA 83: 4533–4543
Carlos TM, Harlan JM (1990) Membrane proteins involved in phagocyte adherence to endothelium. Immunol Rev 114: 5–28
Aasen AO, Smith-Erichsen N, Amundsen E (1983) Plasma kallikrein-kinin system in septicemia. Arch Surg 118: 343–346
Kettleburt IC, Fiers W, Goldber AL (1987) The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors. Proc Natl Acad Sci USA 84: 4273–4278
Lefer AM (1985) Eicosanoids as mediators of ischemia and shock. Fed Proc 44: 275–280
Granger DN, Hollwarth ME, Parks DA (1986) Ischemia-reperfusion injury: role of oxygen derived free radicals. Acta Physiol Scand 548: 47–63
Deitch EA (1989) Simple intestinal obstruction causes bacterial translocation in man. Arch Surg 124: 699–701
Jones WG, Minei JP, Barber AE, Rayburn JL, Fahey TJ, Shires GT (1990) Bacterial translocation and intestinal atrophy after thermal injury and burn wound sepsis. Ann Surg 211: 399–405
Drisk MR, Craven DE, Celli BR (1987) Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine typ 2 blockers. N Engl J Med 317: 1376–1382
Marshall JC, Christou NV, De Santis M (1988) Proximal gastrointestinal flora and systemic infections in the critically ill surgical patient. Surg Forum 38: 89–90
Marshall JC, Christou NV, Horn R (1988) The microbiology of multiple organ failure: the proximal GI-tract as a reservoir of pathogens. Arch Surg 123: 309–315
Garrison RN, Fry DE, Berberich S (1982) Enterococcal bacteremia: clinical implications and determinants of death. Ann Surg 196: 43–47
McCartney AC, Banks JG, Clements GB, Sleigh JD, Tehrani M, Ledingham I (1983) Endotoxinaemia in septic shock: clinical and post mortem correlations. Int Care Med 9: 117–122
Olofsson P, Nylauder G, Olsson P (1986) Endotoxin: routes of transport in experimental peritonitis. Am J Surg 151: 443–446
Stoutenbeek CP, van Saene HKF, Miranda DR, Zandstra DF (1984) The effect of selective decontamination of the digestive tract on colonisation and infection in multiple trauma patients. Int Care Med 10: 185–192
Hartenauer U, Thülig B, Diemer W, Lawin P, Fegeler W, Rehrel R, Ritzerfeld W (1991) Effect of selective flora suppression on colonization, infection, and mortality in critically ill patients: a one-year, prospective consecutive study. Crit Care Med 19: 463–473
Polk HC, Shields CL (1977) Remote organ failure: a valid sign of occult intra-abdominal infection. Surgery 81: 310–312
Hindsdale JG, Jaffe BM (1984) Re-operation for intraabdominal sepsis: indications and results in modern critical care settings. Am Surg 199: 31–36
Norton LW (1985) Does drainage of intraabdominal pus reverse multiple organ failure? Am J Surg 149: 347–350
Meakins JL, Marshall JC (1989) The gut as the motor of multiple system organ failure. In: Marston A, Bulkley GB, Fiddian-Green RG, Haglund UH (eds) Splanchnic ischemia and multiple organ failure, 1st edn. Arnold E, London Melbourne Auckland, pp 339–348
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag/Wien
About this chapter
Cite this chapter
Hasibeder, W., Haisjackl, M., Schwarz, C., Sparr, H., Germann, R., Friesenecker, B. (1992). Das Splanchnikusgebiet im Rahmen des Multiorganversagens. In: Deutsch, E., et al. Multiorganversagen. Intensivmedizinisches Seminar, vol 4. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9201-6_11
Download citation
DOI: https://doi.org/10.1007/978-3-7091-9201-6_11
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82334-7
Online ISBN: 978-3-7091-9201-6
eBook Packages: Springer Book Archive