Abstract
The relationship between extracranial carotid atherosclerosis, transient ischemic attacks and cerebral infarction is similar to that between coronary atherosclerosis and angina pectoris, myocardial infarction and sudden death. The prevalence of internal carotid artery (ICA) stenosis of any degree in subjects devoid of any cerebrovascular symptoms or signs is low in both sexes prior to 65 years of age. It is only 2.4% in males between the ages of 55 and 64 years, but it increases sharply with age, reaching 30.3% for stenosis of less than 50% and 6.1% for stenosis greater than 50% in males aged 75–84 years. The prevalence of minimal lesions (plaques causing less than 15% diameter reduction) is high: 32.1% in males aged 45–54 years and 48.5% in the 75 to 84 year age range. In all studies age is the most important risk factor for carotid atherosclerosis. Hypertension, diabetes mellitus, cigarette smoking and hyperlipidemia have also been associated with increased risk for cerebrovascular atherosclerosis. A recent study (Niederkorn, 1991) found a significant association between fibrinogen levels (as well as age) and the presence of carotid stenosis in a group of 125 asymptomatic subjects. Earlier studies had established a significant correlation between fibrinogen levels and symptomatic carotid artery disease (Lechner, 1987). It has been suggested that elevated fibrinogen may be an independent risk factor for stroke and may have value as a simple screening test to help establish the probability of early atherosclerotic carotid artery disease in asymptomatic patients even in the absence of other classic risk factors (Wilhelmson, 1984). Progression of stenosis (mean follow-up interval 26 months) was associated in Niederkorn’s 1991 report with lower HDL cholesterol levels (average 44.5 ± 13 mg/di) than in subjects showing no interval increase in vessel narrowing (average values 57.9 ± 18 mg/dl).
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References
Adachi B (1928) Das Arteriensystem der Japaner. In: Adachi B (Hrsg) Anatomie der Japaner, Bd 1, 1. Aufl. Verlag der Kaiserlich-Japanischen Universität zu Kyoto, Kyoto
Barnett HJM (1978) Delayed cerebral ischemic episodes distal to occlusion of major cerebral arteries. Neurology 28: 769–774
Barnett HJM, Peerless SJ, Kaufmann JCM (1978) “Stump” of internal carotid artery — a source for further cerebral embolic ischemia. Stroke 9:448–456
Beckett WW, Davis PC, Hoffman JC Jr (1990) Duplex Doppler sonography of the carotid artery: False-positive results in an artery contralateral to an artery with marked stenosis. AJR 155: 1090–1095
Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis (1991) Report from the North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 325: 445–453
Bharadvaj BK, Mabon RF, Giddens DP (1982a) Steady flow in a model of the human bifurcation. Part I: Flow visualization. J Biomech 15: 349–362
Bharadvaj BK, Mabon RF, Giddens DP ( 1982 b) Steady flow in a model of human bifurcation. Part II: Laser — Doppler anemometer measurements. J Biomech 15: 363–378
Blackshear WM Jr, Phillips DJ, Bodily KC, Strandness DE Jr (1980) Ultrasonic demonstration of external and internal carotid patency with common carotid occlusion: a preliminary report. Stroke 3: 249–252
Blackwell E, Merory J, Toole JF, McKinney WM (1977) Doppler ultrasound scanning of the carotid bifurcation. Arch Neurol 34: 145–148
Blackwell DE, McKinney WM, Nunn C, Hirsch G, Sackler JP (1984) Low cost real-time Doppler frequency analysis. Medical Ultrasound 8: 23–29
Blaisdell WF, Clauss RH, Galbraith JG, Imparato AM, Wylie EJ (1969) Joint study of extracranial arterial occlusion. IV. A review of surgical considerations. JAMA 209
Blue SK, McKinney WM, Barnes R, Toole JF (1972) Ultrasonic B-mode scanning for study of extracranial vascular disease. Neurology 22: 1081–1085
Bluth EI, Shyn PB, Sullivan MA, Merritt ChRB (1989) Doppler flow imaging of carotid artery dissection. J Ultrasound Med 8: 149–153
Bluth EI, Stavros AT, Marich KW, Wetzner SM, Aufrichtig D, Baker JD (1988) Carotid duplex sonography: A multicenter recommendation for standardized imaging and Doppler criteria. Radiographics 3
Bo WJ, McKinney WM, Bowden RL (1989) The origin and distribution of vasa vasorum at the bifurcation of the common carotid artery with atherosclerosis. Stroke 20: 1484–1487
Breslau PJ, Knox RA, Phillips DJ, Beach KW, Chikos PM, Thiele BL, Strandness DE Jr (1982) Ultrasonic duplex scanning with spectral analysis in extracranial carotid artery disease. Vascular Diag Therapy 3: 17–22
Brown MS, Kovanen PT, Goldstein JL (1981) Regulation of plasma cholesterol by lipoprotein receptors. Science 212: 628–635
Brown PB, Zwiebel WJ, Call GK (1989) Degree of cervical carotid artery stenosis and hemispheric stroke: Duplex US findings. Radiology 170: 541–543
Cisneros JA, Newhouse VL, Goldberg B (1985) Doppler spectral characterization of flow disturbances in the carotid with the Doppler probe at right angles to the vessel axis. Ultrasound Med Biol 11: 319–328
Clagett GP, Patterson CB, Fisher DF Jr, Fry RE, Eidt JF, Humble TH, Fry WJ (1989) Vein patch versus primary closure for carotid endarterectomy. A randomized prospective study in a selected group of patients. J Vasc Surg 9 (2): 213–223
Craven TE, Ryu JE, Espeland MA, Kahl FR, McKinney WM, Toole JF, et al (1990) Evaluation of the association between carotid artery atherosclerosis and coronary artery stenosis. A case-control study. Circulation 82: 1230–1242
Crissey MM, Bernstein EF (1974) Delayed presentation of carotid intimal tear following blunt craniocervical trauma. Surgery 75: 543–549
Crouse JR, Toole JF, McKinney WM, Dignan MB, Howard G, Kahl FR, McMahan MR, Harpold GH (1987) Risk factors for extracranial carotid artery atherosclerosis. Stroke 6: 990–996
Crowe WJ, Krovetz LJ (1972) Studies of arterial branching in models using flow birefringence. Med Biol Engng 10: 415–426
DeGroote RD, Lynch TG, Jamil Z, Hobson RW (1987) Carotid restenosis: long-term noninvasive follow-up after carotid endarterectomy. Stroke 18: 1031–1036
Douville Y, Johnston KW, Kassam M (1985) Determination of the hemodynamic factors which influence carotid Doppler spectral broadening. Ultrasound Med Biol 11: 417–423
Dyken ML, Klatte E, Kolar OJ, Surgeon C (1974) Complete occlusion of common or internal carotid arteries. Clinical significance. Arch Neurol 30: 343–346
Eckmann A, Kuhn FP, Grönniger J (1986) Postoperative Verlaufskontrolle der A. carotis mit der Duplex-Sonographie. Fortschr Röntgenstr 145: 639–641
Erickson SJ, Newissen MW, Foley WD, Lawson TL, Middleton WD, Quiroz FA, Macrander SJ, Lipchik EO (1989) Stenosis of the internal carotid artery: assessment using color Doppler imaging compared with angiography. AJR 152: 1299–1305
Fei DY, Billian C, Rittgers SE (1988) Flow dynamics in a stenosed carotid bifurcation model — Part I: Basic velocity measurements. Ultrasound Med Biol 14: 21 —31
Fell G, Phillips DJ, Chikos PM, Harley JD, Thiele BL, Strandness DE Jr (1981) Ultrasonic duplex scanning for disease of the carotid artery. Circulation 64: 1191–1195
Födisch HJ (1970) Die Thrombosen der A. carotis and ihrer Äste nach stumpfen Traumen. In: Löhr B, Senning A, Witt AN (Hrsg) Ergebnisse der Chirurgie and Orthopädie 53: 75–98
Fox JA, Hugh AE (1966) Localization of atheroma: A theory based on boundary layer separation. Br Heart J 28: 388–399
Genton E, Barnett HJM, Fields WS, Gent M, Hoak JC (1977) Report of the joint committee for stroke resources XIV: Cerebral ischemia, the role of thrombosis and antithrombotic therapy. Stroke 8: 147–175
Giddens DP, Mabon RF, Cassanova RA (1976) Measurements of disordered flow distal to subtotal vascular stenoses in the thoracic aortas of dogs. Circ Res 39: 112–119
Glover JL, Bendick PJ, Dilly RS, Jackson VP, Reilly MK, Dalsing MC, Robison RJ (1985) Restenosis following carotid endarterectomy. Arch Surg 120: 678–683
Glover JL, Bendick PJ, Jackson VP, Becker GJ, Dilley RS, Holden RW (1984) Duplex ultrasonography, digital subtraction angiography and conventional angiography in assessing carotid atherosclerosis. Arch Surg 119: 664–669
Hallam MJ, Reid J, Cooperberg PL (1989) Color-flow Doppler and conventional Duplex scanning of the carotid bifurcation: Prospective, double-blind, correlative study. AJR 152: 1101–1105
Hass WK, Fields WS, North RR, Kricheff H, Chase NE, Bauer RB (1968) Joint study of extracranial arterial occlusion. II. Arteriography, techniques, sites, and complications. JAMA 203: 159–166
Hennerici M, Freund HJ (1984) Efficacy of CW-Doppler and duplex system examinations for the evaluation of extracranial carotid disease. JCU 12: 155–161
Hertzer NR, Flanagan RA, O’Hara PJ, Beven EG (1986) Surgical versus nonoperative treatment of asymptomatic carotid stenosis. Ann Surg 204: 163–171
Houi K, Mochio S, Isogai Y, Miyamoto Y, Suzuki N (1990) Comparison of color flow and 3D image by computer graphics for the evaluation of carotid disease. Angiology 41 (4): 305–312
Hübsch P, Schwaighofer B, Kamel F, Braunsteiner A, Frühwald F, Pichler W, Trattnig S (1988) Farbcodierte Dopplersonographie der Karotiden. Röntgen Fortschr 149: 189–192
Hutchison KJ, Karpinski E (1985) In vivo demonstration of flow recirculation and turbulence downstream of graded stenoses in canine arteries. J Biomech 18: 285–296
Imparato AM, Riles TS, Gorstein F (1979) The carotid bifurcation plaque: pathologic findings associated with cerebral ischemia. Stroke 10: 238–245
Jacobs NM, Grant EG, Schellinger D, Byrd MC, Richardson JD, Cohan SL (1985) Duplex carotid sonography: Criteria for stenosis, accuracy, and pitfalls. Radiology 154: 385–391
Javid H, Ostermiller WE, Hengesh JW, Dye WS, Hunter JA, Najafi H, Julian OC (1970) Natural history of carotid bifurcation atheroma. Surgery 67: 80–86
Kalman PG, Johnston KW, Zuech P, Kassam M, Potts K (1985) In vitro comparison of alternative methods for quantifying the severity of Doppler spectral broadening for the diagnosis of carotid arterial occlusive disease. Ultrasound Med Biol 11: 435–440
Kassam M, Johnston KW, Cobbold RSC (1985) Quantitative estimation of spectral broadening for the diagnosis of carotid arterial disease: Method and in vitro results. Ultrasound Med Biol 11: 425–433
Keller HM, Valavanis A, Imhof HG, Turina M (1984) Patency of external and internal carotid artery in the presence of an occluded common carotid artery: Noninvasive evaluation with combined cerebrovascular Doppler examination and sequential computertomography. Stroke 1: 149–157
Khalifa AMA, Giddens DP (1981) Characterization and evolution of post-stenotic flow disturbances. J Biomech 14: 279–296
Lapayowker MS, Stauffer HM, Safer JN (1972) Physiologic stasis of roentgenographic contrast material at the carotid artery bifurcation: Possible correlation to atheroma localization. Am J Roentgenol Radium Therm Nucl Med 114: 803–809
Lechner H, Niederkorn K, Suzuki H (1987) Hemorrheologic parameters in correlation to extracranial carotid disease in patients with acute cerebrovascular disorders. Eur Neurol 27: 139–141
Lechner H, Niederkorn K, Suzuki H (1987) Hemorrheologic parameters in correlation to extracranial carotid disease in patients with acute cerebrovascular disorders. Eur Neurol 27: 139–141
Liou RJ, Clark ME, Robertson JM (1981) Three-dimensional simulation of steady flow past a partial stenosis. J Biomech 14: 325–337
Londrey GL, Spadone DP, Hodgson KJ, Ramsey DE, Barkmeier LD, Sumner GS (1991) Does colorflow imaging improve the accuracy of duplex carotid evaluation? J Vasc Surg 13 (5): 569–663
Lo LY, Ford CS, McKinney WM, Toole JF (1986) Asymptomatic bruit, carotid and vertebrobasilar transient ischemic attacks — a clinical and ultrasonic correlation. Stroke 17: 65–68
Lusby RJ, Ferrell LD, Ehrenfeld WK, et al. (1982) Carotid plaque hemorrhage: its role in production of cerebral ischemia. Arch Surg 117: 1479–1488
Lutz RJ, Hsu L, Menawat A, Zrubek J, Edwards K (1983) Comparison of steady and pulsatile flow in a double branching arterial model. J Biomech 16: 753–766
Lynch PR, Bonakdarpour A, Stauffer HM, Heckman JL (1973) Angiographic evidence of stagnant flow zones in the carotid circulation of anesthetized dogs. Invest Radiol 8: 28–32
Malcolm AD, Roach MR (1979) Flow disturbances at the apex and lateral angles of a variety of bifurcation models and their role in development and manifestations of arterial disease. Stroke 10: 335–343
Malcolm AD, Roach MR (1979) Flow disturbances at the apex and lateral angles of a variety of bifurcation models and their role in development and manifestations of arterial disease. Stroke 10: 335–343
Middleton WD, Foley WD, Lawson TL (1988) Color-flow Doppler imaging of carotid abnormalities. AJR 150: 419–425
Middleton WD, Foley WD, Lawson TL (1988) Flow reversal in the normal carotid bifurcation: Color Doppler flow imaging analysis. Radiology 167: 207–210
Middleton WD, Melson GL (1990) The carotid ghost: A color Doppler ultrasound duplication artifact. J Ultrasound Med 9: 487–493
Moore DJ, Sheehan MP, Kolm MS, Russell JB, Sumner DS (1985) Are strokes predictable with noninvasive methods: a five-year follow up of 303 unoperated patients. J Vasc Surg 2: 654–660
Motomiya M, Karino Takeshi (1984) Flow patterns in the human carotid artery bifurcation. Stroke 1: 50–56
Niederkorn K, Homer S, Schmidt R, Fazekas F, Lechner H (1991) Ultrasonic assessment of the prevalence of carotid artery stenosis in asymptomatic volunteers. J Neuroimaging 1: 119–122
Nicholls SC, Phillips DJ, Primozich JF, Lawrence RL, Kohler TR, Rudd TG, Strandness DE Jr (1989) Diagnostic significance of flow separation in the carotid bulb. Stroke 20: 175–182
O’Brien V, Ehrlich LW (1985) Simple pulsatile flow in an artery with a constriction. J Biomech 18: 117–127
O’Donnell TF Jr, Erdoes L, Mackey WC, et al. (1985) Correlation of B-mode ultrasound imaging and arteriography with pathologic findings of carotid endarterectomy. Arch Surg 120: 443–449
Palmaz JC, Hunter G, Carson SN, French SW (1983) Postoperative carotid restenosis due to neointimal fibromuscular hyperplasia. Radiology 148: 669–702
Podore PC, Rob CG, DeWeese JA, Green RM (1981) Chronic common carotid artery occlusion. Stroke 12: 98–100
Polak JF, Dobkin GR, O’Leary DH, Wang AM, Cutler SS (1989) Internal carotid artery stenosis: Accuracy and reproducibility of color-Doppler-assisted duplex imaging. Radiology 173 (3): 793–798
Quill DS, Colgan MP, Sumner DS (1989) Carotid stump syndrome: a colour-coded Doppler flow study. Eur J Vasc Surg 3: 79–83
Rayman R, Kratky RG, Roach MR (1985) Steady flow visualization in a rigid canine aortic cast. J Biomech 18: 863–875
Reilly LM, Lusby RJ, Hughes L, Ferrell LD, Stoney RJ, Ehrenfeld WK (1983) Carotid plaque histology using real-time ultrasonography: clinical and therapeutic implications. Am J Surg 146: 188–193
Rittgers SE, Fei DY (1988) Flow dynamics in a stenosed carotid bifurcation model — Part II: Derived indices. Ultrasound Med Biol 14
Rittgers SE, Thornhill BM, Barnes RW (1983) Quantitative analysis of carotid artery Doppler spectral waveforms: Diagnostic value of parameters. Ultrasound Med Biol 9: 255–264
Robinson ML, Sacks D, Perlmutter GS, Marinelli DL (1988) Diagnostic criteria for carotid duplex sonography. AJR 151: 487–506
Roederer GO, Langlois YE, Jager KA (1984) The natural history of carotid arterial disease in asymptomatic patients with cervical bruits. Stroke 15: 605–613
Schwaighofer BW, Trattnig S (1990) Farbkodierte Dopplersonographie der Arteria carotis. Radiologe 30: 511–515
Sheldon CD, Murie JA, Quin RO (1983) Ultrasonic Doppler spectral broadening in the diagnosis of internal carotid artery stenosis. Ultrasound Med Biol 9: 575–580
Shulak JM, O’Donovan PB, Paushter DM, Lanzieri CF (1989) Color flow Doppler of carotid body paraganglioma. J Ultrasound Med 8 (9): 519–521
Siouffi M, Pellisier R, Farahifar D, Rieu R (1984) The effect of unsteadiness of flow through stenoses and bifurcations. J Biomech 17: 299–315
So EL, Toole JF, Moody DM, Challa VR (1979) Cerebral embolism from septal fibromuscular dysplasia of the common carotid artery. Ann Neurol 6: 75–78
Steinke W, Hennerici M, Aulich A (1988) Doppler Color flow imaging of carotid body tumors. Stroke 11: 1574–1577
Steinke W, Kloetzsch Ch, Hennerici M (1990) Carotid artery disease assessed by color Doppler flow imaging: Correlation with standard Doppler sonography and angiography. Am J Roentgenol 154 (5): 1061–1068
Sterpetti AV, Schultz RD, Feldhaus RJ, Davenport KL, Richardson M, Farina C, Hunter WJ (1988) Ultrasonographic features of carotid plaque and the risk of subsequent neurologic deficits. Surgery 104: 652–660
Sumner DS (1990) Use of color-flow imaging technique in carotid artery disease (Review Article —17 references). Surg Clin North Am 70 (1): 201–211
Tell GS, Howard G, McKinney WM, Toole JF (1989) Cigarette smoking cessation and extracranial carotid atherosclerosis. JAMA 261: 1178–1180
Terwey B, Gahbauer H, Montemayor M, Proussalis A, Zöllner G (1984) Die B-Bild-Sonographie der Karotisbifurkation. Ultraschall 5: 190–201
Trattnig S, Hübsch P, Barton P, Kamel F, Sautner Th, Schwaighofer B, Kretschmer G (1991) Durchgängigkeit der Karotis externa and interna bei Patienten mit Karotis communis Okklusion: Nachweis in der farbkodierten Dopplersonographie. Fortschr Röntgenstr 154: 44–48
Trattnig S, Schwaighofer B, Hübsch P, Kainberger F, Pölzleitner D (1990) Velocity-Variance-Funktion. Zusatzinformation in der farbkodierten Dopplersonographie der Karotiden. Fortschr Röntgenstr 153: 663–668
Trattnig S, Schwaighofer B, Kainberger F, Hübsch P (1990) Flußumkehr in der Karotisbifurkation. Nachweis in der farbkodierten Doppler-Sonographie. Radiologe 30: 516–519
Weibel J, Fields WS (1969) Atlas of arteriography in occlusive cerebrovascular disease. Georg Thieme, Stuttgart
Weinberger J, Marks SJ, Gaul JJ, Goldman B, Schanzer H, Jacobson J, Dikman S (1987) Atherosclerotic plaque at the carotid artery bifurcation: Correlation of ultrasonographic imaging with morphology. J Ultrasound Med 6: 363–366
Widder B, von Reutern GM, Neuerburg-Heusler D (1986) Morphologische und Dopplersonographische Kriterien zur Bestimmung von Stenosierungsgraden an der A. carotis interna. Ultraschall 7: 70–75
Wilhelmson L, Svardsudd K, Korsan-Bengsten K, et al (1984) Fibrinogen as a risk factor for stroke and myocardial infarction. N Engl J Med 311: 501–505
Wylie J, Effency DJ (1979) Surgery of aortic arch branches and vertebral artery. Surg Clin North Am 59: 669–680
Zarins CK, Giddens DP, Bharadvaj BK, Sottiurai VS, Mabon RF, Glagov S (1983) Carotid bifurcation atherosclerosis: Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res 53: 502–514
Zwiebel WJ, Austin CW, Sackett JF, Strother CM (1983) Correlation of high-resolution B-mode and continuous-wave Doppler sonography with arteriography in the diagnosis of carotid stenosis. Radiology 149: 523–532
Zwicker C, Langer M, Mäurer J, Hepp W (1986) Angiomorphologie arteriosklerotischer GefäBveränderungen im Bereich der Karotisbifurkation. Röntgenblätter 39: 209–215
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Trattnig, S., Hübsch, P. (1992). Color-coded Doppler sonography of the carotid arteries. In: Frühwald, F.X.J., Blackwell, D.E. (eds) Atlas of Color-Coded Doppler Sonography. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9195-8_3
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