Summary
The combination of hypoxia plus glucose deprivation or of hypoxia plus lactate induces carrier-mediated outward transport of 3H-noradrenaline in the rat vas deferens. Lactate efflux is higher from atria than from vas deferens. Hence, the much lower contribution by outward transport to the spontaneous efflux of 3H-noradrenaline in vas deferens than atria is likely to be due to a better supply of oxygen (and perhaps also glucose) to the 3H-noradrenaline- storing varicosities in vas deferens than in atria.
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© 1991 Springer-Verlag
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Trendelenburg, U., Russ, H., Schömig, E. (1991). Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities. In: Bönisch, H., Graefe, KH., Langer, S.Z., Schömig, E. (eds) Recent Advances in Neuropharmacology. Journal of Neural Transmission, vol 34. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9175-0_3
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DOI: https://doi.org/10.1007/978-3-7091-9175-0_3
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