Summary
The neuronal noradrenaline transporter was partially purified by means of low and high pressure liquid chromatography using anion exchange, gel filtration and lectin affinity columns. A protein characterized by a molecular weight of 50–53 kilodalton was enriched; it may represent the transporter or a component of it. In addition, a RNA fraction characterized by a mean size of 2 kilobases was isolated from PC12 rat phaeochromocytoma cells and from bovine adrenal medulla; this RNA fraction caused expression of the noradrenaline transporter after microinjection into Xenopus laevis oocytes.
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© 1991 Springer-Verlag
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Bönisch, H., Paulus, G., Martiny-Baron, G., Lingen, B., Coppeneur, D. (1991). Molecular aspects of the neuronal noradrenaline transporter. In: Bönisch, H., Graefe, KH., Langer, S.Z., Schömig, E. (eds) Recent Advances in Neuropharmacology. Journal of Neural Transmission, vol 34. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9175-0_2
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DOI: https://doi.org/10.1007/978-3-7091-9175-0_2
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