Opioid Receptors

  • H. Schmidhammer
Conference paper


The pharmacological concept of receptors, based upon the observation of rigid structure-activity relationships, stereospecificity, and the observation of maximal pharmacological responses goes back to the turn of the century. Almost hundred years ago, Fischer (1894) proposed the lock — key — model for the system enzyme — glycoside. Later, Langley (1909) and Ehrlich (1913) further developed this model which can be applied for receptors as well.


Opioid Receptor Opiate Receptor Narcotic Analgesic Opioid Receptor Antagonist Endogenous Opioid Peptide 
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Copyright information

© Springer-Verlag/Wien 1991

Authors and Affiliations

  • H. Schmidhammer
    • 1
  1. 1.Institute of Organic and Pharmaceutical ChemistryUniversity of InnsbruckInnsbruckAustria

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