Abstract
The pharmacological concept of receptors, based upon the observation of rigid structure-activity relationships, stereospecificity, and the observation of maximal pharmacological responses goes back to the turn of the century. Almost hundred years ago, Fischer (1894) proposed the lock — key — model for the system enzyme — glycoside. Later, Langley (1909) and Ehrlich (1913) further developed this model which can be applied for receptors as well.
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© 1991 Springer-Verlag/Wien
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Schmidhammer, H. (1991). Opioid Receptors. In: Loimer, N., Schmid, R., Springer, A. (eds) Drug Addiction and AIDS. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9173-6_17
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DOI: https://doi.org/10.1007/978-3-7091-9173-6_17
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