Brachytherapy and Hyperthermia: Biological Rationale

  • G. M. Hahn


The purpose of this chapter is to survey the existing literature on effects of heat on cells and on animal tumors, specifically as these relate to clinical use of interstitial hyperthermia used in conjunction with brachytherapy. Biology remains biology, however, so that much of other research on hyperthermia and its interaction with ionizing irradiations remains applicable, even though the research was carried out for purposes not related to the topic of this book. If indeed this is the case (and it seems fairly obvious that it is), then why write a special review chapter? In part, the answer to this question is that there are aspects of hyperthermic biology that are of unique importance for the topic of this volume; in part also, because there is a body of literature that describes experiments that were performed for the specific purpose of exploring aspects of this combined modality. Finally, it seems that a book such as this has to make its formal bow to laboratory science.


Radiat Oncol Biol Phys Biological Rationale Chinese Hamster Cell Interstitial Radiation Human Fibrosarcoma Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag/Wien 1992

Authors and Affiliations

  • G. M. Hahn
    • 1
  1. 1.Department of Radiation OncologyStanford University School of MedicineStanfordUSA

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