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Early Pathomorphological Changes and Intracranial Volume-Pressure: Relations Following the Experimental Saggital Sinus Occlusion

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Brain Edema VIII

Part of the book series: Acta Neurochirurgica ((NEUROCHIRURGICA,volume 51))

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Summary

Saggital sinus occlusion was produced in cats. The intracranial volume-pressure relations were studied using the lumbar infusion tests. Right after occlusion ICP rised from 7.1 ± 1.8 to 12.4 ± 4.1 mmHg. The values of outflow resistance and volume-pressure response increased also and remained significantly unchanged with only slight decrease of the volume-pressure response. The morphometric study of the surface veins showed the dilatation of the veins draining to the occluded saggital sinus for about 10–20%. No signs of the blood-brain barrier disruption were observed.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland

    Z. Czernicki, G. Pawlowski & G. Uchman

  2. Warsaw University of Technology, Warsaw, Poland

    M. Czosnyka

  3. Department of Neurosurgery, Medical Research Centre, Polish Academy of Sciences, Barska 16, 02-325, Warsaw, Poland

    K. Tychmanowicz

Authors
  1. K. Tychmanowicz
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  2. Z. Czernicki
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  3. M. Czosnyka
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  4. G. Pawlowski
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  5. G. Uchman
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Bern, Switzerland

    Hans-J. Reulen

  2. Institut für chirurgische Forschung, Ludwig-Maximilians-Universität, Klinikum Grosshadern, München, Federal Republic of Germany

    Alexander Baethmann

  3. Department of Neurological Surgery, State University of New York at Stony Brook, New York, USA

    Joseph Fenstermacher

  4. Division of Neurosurgery, Medical College of Virginia, Richmond, Virginia, USA

    Anthony Marmarou

  5. Laboratory of Neuropathology and Neuroanatomical Sciences, National Institutes of Health, Bethesda, Maryland, USA

    Maria Spatz

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© 1990 Springer-Verlag

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Tychmanowicz, K., Czernicki, Z., Czosnyka, M., Pawlowski, G., Uchman, G. (1990). Early Pathomorphological Changes and Intracranial Volume-Pressure: Relations Following the Experimental Saggital Sinus Occlusion. In: Reulen, HJ., Baethmann, A., Fenstermacher, J., Marmarou, A., Spatz, M. (eds) Brain Edema VIII. Acta Neurochirurgica, vol 51. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9115-6_78

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  • DOI: https://doi.org/10.1007/978-3-7091-9115-6_78

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9117-0

  • Online ISBN: 978-3-7091-9115-6

  • eBook Packages: Springer Book Archive

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