Summary
Diffusion-weighted MR imaging is a new technique which measures the microscopic motion of water protons. Signal hyperintensity on diffusion-weighted images correlates closely with evidence of ischaemic damage on histopathologic sections. Following occlusion of the middle cerebral artery (MCA), diffusion-weighted images indicate the presence of early pathophysiologic changes occurring first in the basal ganglia and, subsequently, in cortical gray matter within the MCA vascular territory. Diffusion-weighted images also better define the anatomic locus of ischaemic tissue injury than T2-weighted images. Diffusion-weighted imaging thus appears to facilitate early detection and thereby possible therapeutic intervention in patients with acute stroke.
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© 1990 Springer-Verlag
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Sevick, R.J., Kucharczyk, J., Mintorovitch, J., Moseley, M.E., Derugin, N., Norman, D. (1990). Diffusion-Weighted MR Imaging and T2-Weighted MR Imaging in Acute Cerebral Ischaemia: Comparison and Correlation with Histopathology. In: Reulen, HJ., Baethmann, A., Fenstermacher, J., Marmarou, A., Spatz, M. (eds) Brain Edema VIII. Acta Neurochirurgica, vol 51. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9115-6_71
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DOI: https://doi.org/10.1007/978-3-7091-9115-6_71
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