Summary
Using dynamic PET mode and 18FDG, glucose transport in patients with gliomas were investigated. The values for transfer rate constants kl*, k2*, k3*, and glucose consumption were found to be low in the low-grade glioma as compared to those of the high-grade glioma and the contralateral cerebral cortex. The differences were statistically significant with the exception of k2*. There were no statistically significant differences between the high-grade glioma and the contralateral cerebral cortex. In contrast, the distribution volumes k1*/ k2* and k1*/(k2*+k3*) were low in high-grade glioma and the difference between the high-grade glioma and the contralateral cerebral cortex was statistically significant. A difference in k1*/ (k2*+k3*) was noted between the low-grade and the high-grade gliomas. Thus, the distribution volumes are most sensitive for differentiation between high-grade glioma and cerebral cortex.
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© 1990 Springer-Verlag
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Ishikawa, M., Kikuchi, H., Nishizawa, S., Yonekura, Y. (1990). Evaluation of Glucose Transport in Malignant Glioma by PET. In: Reulen, HJ., Baethmann, A., Fenstermacher, J., Marmarou, A., Spatz, M. (eds) Brain Edema VIII. Acta Neurochirurgica, vol 51. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9115-6_56
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DOI: https://doi.org/10.1007/978-3-7091-9115-6_56
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