Therapeutic Effects of Topical Dexamethasone on Experimental Brain Tumours and Peritumoural Brain Oedema

  • Y. Ikeda
  • B. S. Carson
  • D. M. Long
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 51)


Topical application of dexamethasone to brain tumour bed retains its biological effectiveness in controlling peritumoural brain oedema, possibly through the oncolytic mechanism (cytostatic effect). The question rises, whether the sytemic administration of dexamethasone can be duplicated with dexamethasone topically to the brain tumour bed.


Tumour Implantation Brain Water Content Osmotic Pump Teflon Catheter Experimental Brain Tumour 
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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Y. Ikeda
    • 1
  • B. S. Carson
    • 2
  • D. M. Long
    • 2
  1. 1.Department of NeurosurgeryNippon Medical SchoolBunkyo-ku, Tokyo 113Japan
  2. 2.Johns Hopkins University School of MedicineBaltimoreUSA

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