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In vivo Measurement of Brain Water by MRI

  • A. Marmarou
  • P. Fatouros
  • J. Ward
  • A. Appley
  • H. Young
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 51)

Summary

A new method for determining brain tissue water using MRI, developed in the laboratory, has been tested and applied to the clinical setting. To evaluate the accuracy of the technique, samples of human brain tissue were harvested from patients scheduled to undergo surgical removal of tumour and in whom biopsies were required for clinical management. MR determined values from imaging water maps compared favourably with gravimetric measures of samples. From these data, we conclude that accurate non-invasive measures of brain oedema in man are now possible.

Keywords

Magnetic Resonance Imaging Brain Oedema Oedema Formation Human Brain Tissue Brain Water Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Penn RD, Bacus JW (1984) The brain as a sponge: A computed tomographic look at Hakim’s hypothesis. Neurosurgery 14: 670–675PubMedCrossRefGoogle Scholar
  2. 2.
    MacDonald HL, Bell BA, Smith MA, Kean DM, Tocher JL, Douglas RHB, Miller JD, Best JJK (1986) Correlation of human NMR P1 values measured in vivo and brain water content. Br J Radiol 59: 355PubMedCrossRefGoogle Scholar
  3. 3.
    Bell BA, Kean DM, MacDonald HL, Barnett GH, Douglas RHB, Smith MA, McGhee CNJ, Miller JD, Tocher JL, Best JJK (1987) Brain water measured by magnetic resonance imaging. Lancet is 66Google Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • A. Marmarou
    • 3
  • P. Fatouros
    • 1
  • J. Ward
    • 2
  • A. Appley
    • 2
  • H. Young
    • 2
  1. 1.Division of RadiologyMedical College of VirginiaRichmondUSA
  2. 2.Division of NeurosurgeryMedical College of VirginiaRichmondUSA
  3. 3.Division of NeurosurgeryMedical College of VirginiaRichmondUSA

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