Summary
The mechanical filtration coefficient (Lp) of the membrane of cultured glioma cells was determined from the rate of swelling of the cells. The swelling was induced by exposing the cells to distilled water. Assuming that cells swell in a symmetrical manner, Lp was 2.2 × 10−8 cm/s · mmHg, or 1.7 × 10−4 µm/s · cmH2O when calculated from changes of the cell diameter.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Katchalsky A, Curran PF (1967) Nonequilibrium thermodynamics in biophysics. Harvard University Press, Cambridge
Mitchel CC (1980) Filtration coefficients and osmotic reflexion coefficients of the cells of single frog mesenteric capillaries. J Physiol 309: 341–355
Sidel VW, Solomon AK (1957) Entrance of water into human red cells under a osmotic pressure gradient. J Gen Physiol 41: 243–257
Tornita M, Gotoh F, Kobari M (1988) Colloid osmotic pressure of cat brain homogenate separated from autogenous CSF by a copper ferrocyanide membrane. Brain Res 474: 165–173
Tornita M, Gotoh F, Tanahashi N, Kobari M, Terayama Y, Mihara B, Ohta K (1987) Thermodynamic energy for maintaining brain volume and preventing swelling. J Cereb Blood Flow Metabol 7 [Suppl 1]: S 122
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag
About this paper
Cite this paper
Tomita, M. et al. (1990). The Mechanical Filtration Coefficient (Lp) of the Cell Membrane of Cultured Glioma Cells (C6). In: Reulen, HJ., Baethmann, A., Fenstermacher, J., Marmarou, A., Spatz, M. (eds) Brain Edema VIII. Acta Neurochirurgica, vol 51. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9115-6_4
Download citation
DOI: https://doi.org/10.1007/978-3-7091-9115-6_4
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-9117-0
Online ISBN: 978-3-7091-9115-6
eBook Packages: Springer Book Archive