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Transient Effect of Mannitol on Cerebral Blood Flow Following Brain Injury

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Brain Edema VIII

Part of the book series: Acta Neurochirurgica ((NEUROCHIRURGICA,volume 51))

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Summary

CBF and ICP were measured in cats following cerebral cold injury and mannitol infusion. Mannitol was found to reduce the intracranial hypertension caused by the injury. The restoration of CBF and ICP was of short duration and was followed by a reduction of CBF and elevation of ICP. A repeated restoration of CBF by a second dose of mannitol was followed by a more severe impairment of CBF. The prolonged beneficial effect of mannitol on CBF after brain injury has to be reassessed.

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References

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Experimental Research Laboratory, Beilinson Medical Center, Petah Tiqva, Israel

    E. Shalmon & E. Reichenthal

  2. Department of Neurosurgery, Experimental Research Laboratory, Beilinson Medical Center, Petah Tiqva, 49 100, Israel

    Dr. T. Kaspi

Authors
  1. E. Shalmon
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  2. E. Reichenthal
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  3. Dr. T. Kaspi
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Bern, Switzerland

    Hans-J. Reulen

  2. Institut für chirurgische Forschung, Ludwig-Maximilians-Universität, Klinikum Grosshadern, München, Federal Republic of Germany

    Alexander Baethmann

  3. Department of Neurological Surgery, State University of New York at Stony Brook, New York, USA

    Joseph Fenstermacher

  4. Division of Neurosurgery, Medical College of Virginia, Richmond, Virginia, USA

    Anthony Marmarou

  5. Laboratory of Neuropathology and Neuroanatomical Sciences, National Institutes of Health, Bethesda, Maryland, USA

    Maria Spatz

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© 1990 Springer-Verlag

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Shalmon, E., Reichenthal, E., Kaspi, T. (1990). Transient Effect of Mannitol on Cerebral Blood Flow Following Brain Injury. In: Reulen, HJ., Baethmann, A., Fenstermacher, J., Marmarou, A., Spatz, M. (eds) Brain Edema VIII. Acta Neurochirurgica, vol 51. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9115-6_39

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  • DOI: https://doi.org/10.1007/978-3-7091-9115-6_39

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9117-0

  • Online ISBN: 978-3-7091-9115-6

  • eBook Packages: Springer Book Archive

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