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Venous and Cerebrospinal Fluid Outflow in Patients with Brain Swelling and Oedema

  • A. R. Shakhnovich
  • A. Y. Razumovsky
  • S. S. Gasparjan
  • V. I. Ozerova
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 51)

Summary

67 patients with benign intracranial hypertension (BIH) and 44 with normal pressure hydrocephalus (NPH) were examined by employment of infusion tests. Brain swelling (decrease of ventricular size with normal or increased brain tissue density) was a characteristic feature of BIH. It may result from venous outflow disturbances leading to vascular engorgement. But later, the process appears to be independent from the increase of the dural sinus pressure. This was normal in patients with BIH and NPH. Despite absorption disturbances there was a strong positive correlation in NPH between cerebrospinal fluid- and dural sinus pressure, while in BIH such a correlation was absent. The data confirm a pathogenesis of brain swelling in BIH as an obstacle to venous outflow at the level of the bridging veins and venous lacunae, however, not at the level of the durai sinuses.

Keywords

Cerebral Blood Volume Venous Outflow Normal Pressure Hydrocephalus Dural Sinus Normal Pressure Hydrocephalus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Auer LM, Ishiyama N (1986) Cerebrovascular response to elevated intracranial pressure. In: Miller JD, Teasdale GM, Rowan JO et al (eds) Intracranial pressure VI. Springer, Berlin Heidelberg, New York, pp 399–403Google Scholar
  2. 2.
    Grant R, Condon B, Rowan J, Teasdale GM (1989) Benign intracranial hypertension: Brain swelling and cranial CSF volume. In: Hoff JT, Betz AL (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York, pp 344–345CrossRefGoogle Scholar
  3. 3.
    Junk L (1986) Benign intracranial hypertension and normal pressure hydrocephalus: theoretical considerations. In: Miller JD, Teasdale GM, Rowan JO et al (eds) Intracranial pressure VI. Springer, Berlin Heidelberg New York, pp 447–450Google Scholar
  4. 4.
    Langfitt TW, Zimmerman RA (1985) Imaging and in vivo biochemistry of the brain in head injury. In: Becker DP, Povlishock JT (eds) Central nervous system trauma. Status report 1985. NIH, USA, pp 53–63Google Scholar
  5. 5.
    Milhorat TH, Clark RG et al (1970) Structural, ultrastructural and permeability changes in the ependyma and surrounding brain favouring equilibration in progressive hydrocephalus. Arch Neurol 22: 297–497CrossRefGoogle Scholar
  6. 6.
    Nakagawa Y, Tsuru M, Furuse M et al (1974) Site and mechanisms for compression of the venous system during experimental intracranial hypertension. J Neurosurg 41: 427–434PubMedCrossRefGoogle Scholar
  7. 7.
    Portnoy HD, Crossant PD (1976) A practical method for measuring hydrodynamics of cerebrospinal fluid. Surg Neurol 5: 273–277PubMedGoogle Scholar
  8. 8.
    Sahar A, Hochwald G, Ransohoff J (1970) Cerebrospinal fluid and cranial sinus pressures—Relationship in normal and hydrocephalic cats. Arch Neurol 23: 413–418PubMedCrossRefGoogle Scholar
  9. 9.
    Shakhnovich AR, Razumovsky AY, Gasparian SS et al (1986) Elastic properties of the cerebrospinal system and hydrodynamic of the CSF in patients with intracranial hypertension. In: Miller JD, Teasdale GM, Rowan JO et al (eds) Intracranial pressure VI. Springer, Berlin Heidelberg New York, pp 89–95Google Scholar
  10. 10.
    Shulman K, Yarnell P, Ransohoff J (1964) Dural sinus pressure. In normal and hydrocephalic dogs. Arch Neurol 10: 575–580Google Scholar
  11. 11.
    Sklar FH, Beyer CW, Hagler JH et al (1980) The pressure volume function of brain elasticity and its relationship with ventricular size. In: Shulman K, Marmarou A, Miller JD et al (eds) Intra-cranial pressure IV. Springer, Berlin Heidelberg New York, pp 81–84Google Scholar
  12. 12.
    Soelberg-Sorensen P, Thomsen C, Gjerris F, Schmidt JF, Henriksen 0 (1989) Increased brain water self diffusion measured by magnetic resonance scanning in patients with pseudotumour cerebri. In: Hoff JT, Betz AL (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York, pp 419–421CrossRefGoogle Scholar
  13. 13.
    Szewzykowsky J, Slivka ST, Kunicki A et al (1977) A fast method of estimating the elastance of the intracranial system. J Neurosurg 47: 19–26CrossRefGoogle Scholar
  14. 14.
    Ueda Y, Nagai H, Kamiya K, Mase M (1989) Significance of cortical venous pulse pressure and superior sagittal sinus pulse pressure on ICP-pulse pressure. In: Hoff JT, Betz AL (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York, pp 166–168CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • A. R. Shakhnovich
    • 1
  • A. Y. Razumovsky
    • 1
  • S. S. Gasparjan
    • 1
  • V. I. Ozerova
    • 1
  1. 1.Burdenko Neurosurgical InstituteMoscowUSSR

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