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Amine oxidase activities in bovine lung

  • J. M. Lizcano
  • D. Balsa
  • K. F. Tipton
  • M. Unzeta
Conference paper
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 32)

Summary

The subcellular distributions of amine oxidase activities MAO-A, MAO-B and SSAO, in bovine lung have been determined. MAO activities are largely confined to the mitochondria whereas SSAO activity is concentrated in the microsomal fraction.

The contribution of different type of amine oxidase present in the microsomal fraction to the metabolism of the benzylamine, tyramine, phenylethylamine, tryptamine and dopamine were determined. The kinetic constants towards benzylamine showed SSAO to have a higher affinity than MAO-B, and the comparison of the Vmax/Km relationship for both enzymes indicated that benzylamine would be oxidised more efficiently by SSAO than by MAO-B.

Keywords

Brown Adipose Tissue Microsomal Fraction Amine Oxidase Bovine Lung SSAO Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • J. M. Lizcano
    • 1
  • D. Balsa
    • 1
  • K. F. Tipton
    • 1
  • M. Unzeta
    • 1
  1. 1.Departament Bioquímica i Biologia Molecular, Facultat de MedicinaUniversität Autonoma de BarcelonaBellaterra (Barcelona)Spain

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